Reviewed, UniProtKB/Swiss-Prot A0KTP8 (RLMG_SHESA)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase G
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rlmG
    23S rRNA m2G1835 methyltransferase

Gene names

Name:	rlmG
Ordered Locus Names:	Shewana3_0932

Organism

Shewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]

Taxonomic identifier

94122 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01859
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 377	377	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366516

Sequences

	Sequence		Length	Mass (Da)
	A0KTP8-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 1924115ADFB2EDBD	FASTA	377	41,565
	10 20 30 40 50 60 MTTQFSVAGI ELELFRYPAS QESNLQAWDA ADEHLINTLV EGGQTAVPTA IINDSFGALS 70 80 90 100 110 120 CALSRLNPDW PLNVETDART SFLGAEQNHH RNQLPMDNLT RFTSRDALPC DLALVLMKLP 130 140 150 160 170 180 KNLTYFAHQL MRLSQVLPAG CKVLVGAKAK SINASLLEVF ATHLGPASAS LAWKKTRVIT 190 200 210 220 230 240 CISDGKPRAL PKEVTWDIPE FNLHISNLSN VFAANKLDIG ARIMLDNLPQ GDFKTIVDLG 250 260 270 280 290 300 CGNGVLGLRA AQLYPNADIH FIDDSEMAVA SAKANWANNQ LPAEKGHFHW DDCMTHLPDG 310 320 330 340 350 360 VEPDLVLCNP PFHQGEAITD HIAWQMFLDA RRRLKNGGIL HIVGNRHLAY HVKLQRLFKN 370 CTTVASNGKF VILQAQK

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. ANA-3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000469 Genomic DNA. Translation: ABK47167.1.
RefSeq	YP_868573.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0KTP8.
Genome annotation databases
GeneID	4478858.
GenomeReviews	Gene locus Shewana3_0932 in contig CP000469_GR.
KEGG	shn:Shewana3_0932.
NMPDR	fig|94122.5.peg.1058.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NRHLGYH.
Family and domain databases
HAMAP	MF_01859. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_SHESA

Accession

Primary (citable) accession number: A0KTP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	December 12, 2006
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)