A0KS72 (FIS_SHESA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-binding protein fis

Gene names

Name:	fis
Ordered Locus Names:	Shewana3_0398

Organism

Shewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]

Taxonomic identifier

94122 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters By similarity. HAMAP-Rule MF_00166
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_00166
Sequence similarities	Belongs to the transcriptional regulatory fis family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Molecular function	Activator
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	DNA-binding protein fis HAMAP-Rule MF_00166		PRO_1000023341
Regions
	DNA binding	77 – 96	20	H-T-H motif By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0KS72 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 4FD2982815CDCFA8	FASTA	101	11,390
	10 20 30 40 50 60 MFDQTTNTEV HQLTVGKIET ANGTIKPQLL RDAVKRAVTN FFAQLDGQEA QEVYEMVLSE 70 80 90 100 VEAPLLDIIM QHTRGNQTRA ANMLGINRGT LRKKLKKYGM N

References

[1]

"Complete sequence of chromosome 1 of Shewanella sp. ANA-3." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ANA-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000469 Genomic DNA. Translation: ABK46641.1.
RefSeq	YP_868047.1. NC_008577.1.
3D structure databases
ProteinModelPortal	A0KS72.
SMR	A0KS72. Positions 24-101.
ModBase	Search...
Protein-protein interaction databases
STRING	94122.Shewana3_0398.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK46641; ABK46641; Shewana3_0398.
GeneID	4479305.
KEGG	shn:Shewana3_0398.
PATRIC	23568372. VBISheSp134792_0646.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2901.
HOGENOM	HOG000256331.
KO	K03557.
OMA	HNQTRAA.
ProtClustDB	PRK00430.
Enzyme and pathway databases
BioCyc	SSP94122:GJ9K-419-MONOMER.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
HAMAP	MF_00166. DNA-binding_Fis.
InterPro	IPR005412. Fis_DNA-bd. IPR009057. Homeodomain-like. IPR002197. HTH_Fis. [Graphical view]
Pfam	PF02954. HTH_8. 1 hit. [Graphical view]
PIRSF	PIRSF002097. DNA-binding_Fis. 1 hit.
PRINTS	PR01591. DNABINDNGFIS. PR01590. HTHFIS.
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FIS_SHESA

Accession

Primary (citable) accession number: A0KS72

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	May 29, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program