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A0KRL0 (EFTU_SHESA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf1
Ordered Locus Names:Shewana3_0185, Shewana3_0197
OrganismShewanella sp. (strain ANA-3) [Complete proteome] [HAMAP]
Taxonomic identifier94122 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000337533

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
A0KRL0 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 22C63F111BB0FC0A

FASTA39443,358
        10         20         30         40         50         60 
MAKAKFERNK PHVNVGTIGH VDHGKTTLTA AISHVLAKTY GGEAKDFSQI DNAPEERERG 

        70         80         90        100        110        120 
ITINTSHIEY DTPTRHYAHV DCPGHADYVK NMITGAAQMD GAILVVASTD GPMPQTREHI 

       130        140        150        160        170        180 
LLSRQVGVPF IIVFMNKCDM VDDAELLELV EMEVRELLSE YDFPGDDLPV IQGSALKALE 

       190        200        210        220        230        240 
GEPEWEAKII ELAAALDSYI PEPERDIDKP FLMPIEDVFS ISGRGTVVTG RVERGIVRVG 

       250        260        270        280        290        300 
DEVEIVGIRA TTKTTCTGVE MFRKLLDEGR AGENCGILLR GTKRDDVERG QVLSKPGSIN 

       310        320        330        340        350        360 
PHTTFESEVY VLSKEEGGRH TPFFKGYRPQ FYFRTTDVTG TIELPEGVEM VMPGDNIKMK 

       370        380        390 
VTLICPIAMD EGLRFAIREG GRTVGAGVVA KIFA 

« Hide

References

[1]"Complete sequence of chromosome 1 of Shewanella sp. ANA-3."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Newman D., Salticov C., Konstantinidis K., Klappenback J., Tiedje J., Richardson P.
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ANA-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000469 Genomic DNA. Translation: ABK46429.1.
CP000469 Genomic DNA. Translation: ABK46441.1.
RefSeqYP_867835.1. NC_008577.1.
YP_867847.1. NC_008577.1.

3D structure databases

ProteinModelPortalA0KRL0.
SMRA0KRL0. Positions 10-394.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING94122.Shewana3_0197.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK46429; ABK46429; Shewana3_0185.
ABK46441; ABK46441; Shewana3_0197.
GeneID4477957.
4477969.
KEGGshn:Shewana3_0185.
shn:Shewana3_0197.
PATRIC23567916. VBISheSp134792_0426.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAVTPHTEF.
OrthoDBEOG6R5C6X.
ProtClustDBPRK00049.

Enzyme and pathway databases

BioCycSSP94122:GJ9K-199-MONOMER.
SSP94122:GJ9K-211-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_SHESA
AccessionPrimary (citable) accession number: A0KRL0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 12, 2006
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families