ID   DEOC_AERHH              Reviewed;         257 AA.
AC   A0KPE4;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Deoxyribose-phosphate aldolase;
DE            EC=4.1.2.4;
DE   AltName: Full=Phosphodeoxyriboaldolase;
DE            Short=Deoxyriboaldolase;
DE            Short=DERA;
GN   Name=deoC; OrderedLocusNames=AHA_3690;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-
CC       glyceraldehyde 3-phosphate + acetaldehyde.
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-D-ribose 1-phosphate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the deoC/fbaB aldolase family. DeoC type 2
CC       subfamily.
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DR   EMBL; CP000462; ABK36815.1; -; Genomic_DNA.
DR   RefSeq; YP_858145.1; -.
DR   SMR; A0KPE4; 1-248.
DR   GeneID; 4488016; -.
DR   GenomeReviews; CP000462_GR; AHA_3690.
DR   KEGG; aha:AHA_3690; -.
DR   TIGR; AHA_3690; -.
DR   OMA; A0KPE4; CKEACGD.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:HAMAP.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:HAMAP.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   HAMAP; MF_00592; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR011343; DeoC.
DR   InterPro; IPR002915; DeoC/AroFGH_arch.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR10889; DeoC; 1.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF001357; DeoC; 1.
DR   TIGRFAMs; TIGR00126; deoC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Schiff base.
FT   CHAIN         1    257       Deoxyribose-phosphate aldolase.
FT                                /FTId=PRO_1000072592.
FT   ACT_SITE    166    166       Schiff-base intermediate with
FT                                acetaldehyde (By similarity).
FT   ACT_SITE    198    198       By similarity.
SQ   SEQUENCE   257 AA;  27359 MW;  110C82AD8682F609 CRC64;
     MTDLKLAAQR ALNLMDLTTL NDDDTDQKVI DLCRKAKSPA GLTAAVCIYP RFIPIARKTL
     REIGAADVRI ATVTNFPHGN DDIEIAVAET RAAVAYGADE VDVVFPYRAF MAGNEQVGFD
     LVKACKEACG SQALLKVIIE TGELKEEALI RRASEISIDA GADFIKTSTG KVPVNATPEA
     ARIMMEVIKA KNPKVGFKPA GGVKDAAVAG QYLAMAEEIL GKDWVSARTF RFGASSLLAS
     LLATLGHGDK PANTSGY
//