Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphopentomutase

Gene

deoB

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotation
2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotation

Cofactori

Mn2+UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Phosphopentomutase (deoB)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi10ManganeseUniRule annotation1
Metal bindingi306ManganeseUniRule annotation1
Metal bindingi342ManganeseUniRule annotation1
Metal bindingi343ManganeseUniRule annotation1
Metal bindingi354ManganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyciAHYD380703:G1G7B-3685-MONOMER
UniPathwayiUPA00087; UER00173

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphopentomutaseUniRule annotation (EC:5.4.2.7UniRule annotation)
Alternative name(s):
PhosphodeoxyribomutaseUniRule annotation
Gene namesi
Name:deoBUniRule annotation
Ordered Locus Names:AHA_3688
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000756 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000463811 – 402PhosphopentomutaseAdd BLAST402

Proteomic databases

PRIDEiA0KPE2

Interactioni

Protein-protein interaction databases

STRINGi380703.AHA_3688

Structurei

3D structure databases

ProteinModelPortaliA0KPE2
SMRiA0KPE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphopentomutase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CZG Bacteria
COG1015 LUCA
HOGENOMiHOG000008159
KOiK01839
OMAiCHASGTE

Family and domain databases

CDDicd16009 PPM, 1 hit
Gene3Di3.30.70.1250, 1 hit
3.40.720.10, 2 hits
HAMAPiMF_00740 Phosphopentomut, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR010045 DeoB
IPR006124 Metalloenzyme
IPR024052 Phosphopentomutase_DeoB_cap_sf
PANTHERiPTHR21110 PTHR21110, 1 hit
PfamiView protein in Pfam
PF01676 Metalloenzyme, 1 hit
PIRSFiPIRSF001491 Ppentomutase, 1 hit
SUPFAMiSSF143856 SSF143856, 1 hit
SSF53649 SSF53649, 2 hits
TIGRFAMsiTIGR01696 deoB, 1 hit

Sequencei

Sequence statusi: Complete.

A0KPE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRTFILMMD SFGIGAAADA DKFGDVGANT LGHIAKACAA GEIEGRGALN
60 70 80 90 100
LPNLSKLGLG HAGELASGTF PAGLNKDIDV VGAYGFAQEL SSGKDTPSGH
110 120 130 140 150
WEIAGVPVLF EWGYFHDHHN SFPQELLDAI VEKAGLPGYL GNCHASGTQV
160 170 180 190 200
LDDLGEEHMR TGKPILYTSA DSVFQIACHE ETYGLEKLYE LCHIVRELLE
210 220 230 240 250
PYNIGRVIAR PFVGSGKGNF KRTGNRHDYS VLPPAPTVLD YMKEAGGQVV
260 270 280 290 300
SIGKIADIYA QQGITKQVKG TGLTELWDRT LEEVKAAGDQ TIVFTNFVDF
310 320 330 340 350
DSSYGHRRDV KGYADALEYF DSRLPELFEL LEDGDVVVLT ADHGCDPTWG
360 370 380 390 400
GTDHTREYIP VLFYGKPVKA GSVGRRETFA DIGQSIAAYH GLPKLAYGTS

FL
Length:402
Mass (Da):43,552
Last modified:December 12, 2006 - v1
Checksum:i982585D84E97BD38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA Translation: ABK37158.1
RefSeqiWP_011707411.1, NC_008570.1
YP_858143.1, NC_008570.1

Genome annotation databases

EnsemblBacteriaiABK37158; ABK37158; AHA_3688
GeneIDi4488014
KEGGiaha:AHA_3688
PATRICifig|380703.7.peg.3666

Similar proteinsi

Entry informationi

Entry nameiDEOB_AERHH
AccessioniPrimary (citable) accession number: A0KPE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: June 20, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health