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Protein

tRNA1(Val) (adenine(37)-N6)-methyltransferase

Gene

AHA_3669

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 37 of tRNA1(Val) (anticodon cmo5UAC).UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(37) in tRNA1(Val) = S-adenosyl-L-homocysteine + N6-methyladenine(37) in tRNA1(Val).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processtRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciAHYD380703:G1G7B-3666-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA1(Val) (adenine(37)-N6)-methyltransferaseUniRule annotation (EC:2.1.1.223UniRule annotation)
Alternative name(s):
tRNA m6A37 methyltransferaseUniRule annotation
Gene namesi
Ordered Locus Names:AHA_3669
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000756 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003873361 – 236tRNA1(Val) (adenine(37)-N6)-methyltransferaseAdd BLAST236

Interactioni

Protein-protein interaction databases

STRINGi380703.AHA_3669

Structurei

3D structure databases

ProteinModelPortaliA0KPC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107S47 Bacteria
COG4123 LUCA
HOGENOMiHOG000283147
KOiK15460
OMAiDKCAMKV

Family and domain databases

HAMAPiMF_01872 tRNA_methyltr_YfiC, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
IPR022882 tRNA_adenine-N6_MeTrfase
PfamiView protein in Pfam
PF05175 MTS, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0KPC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRNSGFTFK QFHVDHDRCA MKVGTDGILL GAWAPVTNAR RVLDIGSGSG
60 70 80 90 100
LIALMLAQRS PADCRIDAVE LDSNAARQAR ENAAASPWHE RVTVIESAIQ
110 120 130 140 150
TYQATPYDLI VSNPPYFVAG QSFRDPARAL ARHTGGLDSR DLLAACDRLL
160 170 180 190 200
APNGEVALVV PTAMADEILC ISADYDLHAV CYTAVITRAG KEANRVLLRL
210 220 230
GRGLNKCEQG EIVIHSADGT YSDRYIQLTS PFYLKM
Length:236
Mass (Da):25,649
Last modified:December 12, 2006 - v1
Checksum:i40EB3978AB345E08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA Translation: ABK36818.1
RefSeqiWP_011707393.1, NC_008570.1
YP_858125.1, NC_008570.1

Genome annotation databases

EnsemblBacteriaiABK36818; ABK36818; AHA_3669
GeneIDi4487751
KEGGiaha:AHA_3669
PATRICifig|380703.7.peg.3645

Similar proteinsi

Entry informationi

Entry nameiTRMN6_AERHH
AccessioniPrimary (citable) accession number: A0KPC4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: December 12, 2006
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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