A0KP36 (CYSD_AERHH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	AHA_3567

Organism

Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]

Taxonomic identifier

380703 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000008951

Sequences

	Sequence		Length	Mass (Da)
	A0KP36 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 635ED4A0EEDB0D1D	FASTA	302	35,094
	10 20 30 40 50 60 MDRERLTHLQ QLEAESIHII REVAAEFENP VMMYSIGKDS SVMLHLARKA FYPGKIPFPL 70 80 90 100 110 120 LHVDTDWKFK EMIKFRDETA RKYGLDLIVH KNPDGLAMGI NPFVHGSGKH TDIMKTEGLK 130 140 150 160 170 180 QALNKYGFDA AFGGARRDEE KSRAKERVYS FRDKSHRWDP KNQRPELWRV YNSQVNKGES 190 200 210 220 230 240 IRVFPLSNWT ELDIWQYIYL ENIDIVPLYF AAMRPVVERN GIKIMVDDER MPIGPEDEVK 250 260 270 280 290 300 QELVRFRTLG CYPLTGAIES AATTLPEIIE EMLLTTSSER QGRLIDHDQA GSMEQKKRQG YF

References

[1]

"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades." Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F. J. Bacteriol. 188:8272-8282(2006) [PubMed: 16980456] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 7966 / NCIB 9240.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000462 Genomic DNA. Translation: ABK38235.1.
RefSeq	YP_858037.1. NC_008570.1.
3D structure databases
ProteinModelPortal	A0KP36.
SMR	A0KP36. Positions 4-212.
ModBase	Search...
Protein-protein interaction databases
STRING	A0KP36.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4488262.
GenomeReviews	Gene locus AHA_3567 in contig CP000462_GR.
KEGG	aha:AHA_3567.
PATRIC	20784782. VBIAerHyd135212_3554.
TIGR	AHA_3567.
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	NTEISKG.
PhylomeDB	A0KP36.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	AHYD196024:AHA_3567-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_AERHH

Accession

Primary (citable) accession number: A0KP36

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program