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A0KNY4 (FIS_AERHH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-binding protein Fis
Gene names
Name:fis
Ordered Locus Names:AHA_3511
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas

Protein attributes

Sequence length98 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters By similarity. HAMAP-Rule MF_00166

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00166

Sequence similarities

Belongs to the transcriptional regulatory Fis family.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   LigandDNA-binding
   Molecular functionActivator
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9898DNA-binding protein Fis HAMAP-Rule MF_00166
PRO_1000023320

Regions

DNA binding74 – 9320H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
A0KNY4 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 8A92F8A109363408

FASTA9811,170
        10         20         30         40         50         60 
MFEQTLTSDA LVTTTHNHAA EPTQRPLRDS VQQALRNYLA QLNGQEVIDL YDMVLSEVEA 

        70         80         90 
PMLDVIMQYT RGNQTRAAVM MGINRGTLRK KLKRYGMN 

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 7966 / NCIB 9240.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000462 Genomic DNA. Translation: ABK36227.1.
RefSeqYP_857985.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KNY4.
SMRA0KNY4. Positions 1-98.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING380703.AHA_3511.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK36227; ABK36227; AHA_3511.
GeneID4488487.
KEGGaha:AHA_3511.
PATRIC20784664. VBIAerHyd135212_3499.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2901.
HOGENOMHOG000256331.
KOK03557.
OMAMSDNANL.
OrthoDBEOG67HJXZ.
ProtClustDBPRK00430.

Enzyme and pathway databases

BioCycAHYD380703:GH2M-3511-MONOMER.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
HAMAPMF_00166. DNA_binding_Fis.
InterProIPR005412. Fis_DNA-bd.
IPR009057. Homeodomain-like.
IPR002197. HTH_Fis.
[Graphical view]
PfamPF02954. HTH_8. 1 hit.
[Graphical view]
PIRSFPIRSF002097. DNA-binding_Fis. 1 hit.
PRINTSPR01591. DNABINDNGFIS.
PR01590. HTHFIS.
SUPFAMSSF46689. SSF46689. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFIS_AERHH
AccessionPrimary (citable) accession number: A0KNY4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families