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A0KNY4

- FIS_AERHH

UniProt

A0KNY4 - FIS_AERHH

Protein

DNA-binding protein Fis

Gene

fis

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi74 – 9320H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciAHYD380703:GH2M-3511-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-binding protein FisUniRule annotation
    Gene namesi
    Name:fisUniRule annotation
    Ordered Locus Names:AHA_3511
    OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
    Taxonomic identifieri380703 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
    ProteomesiUP000000756: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 9898DNA-binding protein FisPRO_1000023320Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi380703.AHA_3511.

    Structurei

    3D structure databases

    ProteinModelPortaliA0KNY4.
    SMRiA0KNY4. Positions 1-98.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the transcriptional regulatory Fis family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2901.
    HOGENOMiHOG000256331.
    KOiK03557.
    OMAiQTKAAKF.
    OrthoDBiEOG67HJXZ.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    HAMAPiMF_00166. DNA_binding_Fis.
    InterProiIPR005412. Fis_DNA-bd.
    IPR009057. Homeodomain-like.
    IPR002197. HTH_Fis.
    [Graphical view]
    PfamiPF02954. HTH_8. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002097. DNA-binding_Fis. 1 hit.
    PRINTSiPR01591. DNABINDNGFIS.
    PR01590. HTHFIS.
    SUPFAMiSSF46689. SSF46689. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A0KNY4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFEQTLTSDA LVTTTHNHAA EPTQRPLRDS VQQALRNYLA QLNGQEVIDL   50
    YDMVLSEVEA PMLDVIMQYT RGNQTRAAVM MGINRGTLRK KLKRYGMN 98
    Length:98
    Mass (Da):11,170
    Last modified:December 12, 2006 - v1
    Checksum:i8A92F8A109363408
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000462 Genomic DNA. Translation: ABK36227.1.
    RefSeqiYP_857985.1. NC_008570.1.

    Genome annotation databases

    EnsemblBacteriaiABK36227; ABK36227; AHA_3511.
    GeneIDi4488487.
    KEGGiaha:AHA_3511.
    PATRICi20784664. VBIAerHyd135212_3499.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000462 Genomic DNA. Translation: ABK36227.1 .
    RefSeqi YP_857985.1. NC_008570.1.

    3D structure databases

    ProteinModelPortali A0KNY4.
    SMRi A0KNY4. Positions 1-98.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 380703.AHA_3511.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK36227 ; ABK36227 ; AHA_3511 .
    GeneIDi 4488487.
    KEGGi aha:AHA_3511.
    PATRICi 20784664. VBIAerHyd135212_3499.

    Phylogenomic databases

    eggNOGi COG2901.
    HOGENOMi HOG000256331.
    KOi K03557.
    OMAi QTKAAKF.
    OrthoDBi EOG67HJXZ.

    Enzyme and pathway databases

    BioCyci AHYD380703:GH2M-3511-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    HAMAPi MF_00166. DNA_binding_Fis.
    InterProi IPR005412. Fis_DNA-bd.
    IPR009057. Homeodomain-like.
    IPR002197. HTH_Fis.
    [Graphical view ]
    Pfami PF02954. HTH_8. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002097. DNA-binding_Fis. 1 hit.
    PRINTSi PR01591. DNABINDNGFIS.
    PR01590. HTHFIS.
    SUPFAMi SSF46689. SSF46689. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 7966 / NCIB 9240.

    Entry informationi

    Entry nameiFIS_AERHH
    AccessioniPrimary (citable) accession number: A0KNY4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3