Reviewed, UniProtKB/Swiss-Prot A0KNE8 (GLMM_AERHH)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	AHA_3310

Organism

Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]

Taxonomic identifier

380703 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	444 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 444	444	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000305632
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	240	1	Magnesium By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0KNE8-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 0F69EA63E0ECEEE1	FASTA	444	47,638
	10 20 30 40 50 60 MARKYFGTDG VRGKVGEYPI TPDFVMKLGW AAGKVLSKKG TRKVLIGKDT RISGYMLESA 70 80 90 100 110 120 LEAGLSAAGL KAILMGPMPT PAVAYLTRTF RAEAGIVISA SHNPYYDNGI KFFSADGTKL 130 140 150 160 170 180 PDEVEMAIEA ELDHELKCVE SAELGKALRI DDAAGRYIEF CKSTFPSNLS LEGLKMVVDC 190 200 210 220 230 240 GHGATYHIAP SVFRELGAEV IAIGCSPDGL NINDGVGSTA PEALAAKVLE CKADLGVAFD 250 260 270 280 290 300 GDGDRLVMVD NTGYIIDGDE ILYIIARDAL RNGRLKGGVV GTLMANMGLE LALQTLGIPF 310 320 330 340 350 360 ARAKVGDRYV LEMMNEKGWR IGGENSGHII CLDQTTTGDG IVAALQVLTA ICTAEMPLAK 370 380 390 400 410 420 LRSGMNKFPQ VLVNVRFAEG RDPLAADAVQ QEVAKVEQEL AGRGRVLLRK SGTEPLIRVM 430 440 VEGEHEQQVR DMAQRIAQQV ESAF

References

[1]

"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades." Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F. J. Bacteriol. 188:8272-8282(2006) [PubMed: 16980456] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000462 Genomic DNA. Translation: ABK38205.1.
RefSeq	YP_857799.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0KNE8.
Genome annotation databases
GeneID	4490972.
GenomeReviews	Gene locus AHA_3310 in contig CP000462_GR.
KEGG	aha:AHA_3310.
TIGR	AHA_3310.
Phylogenomic databases
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 1 hit.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_AERHH

Accession

Primary (citable) accession number: A0KNE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	December 12, 2006
Last modified:	November 3, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)