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A0KMM0 (A0KMM0_AERHH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Homoserine kinase EMBL ABK38756.1
EC=2.7.1.39 EMBL ABK38756.1
Gene names
Name:thrB EMBL ABK38756.1
Ordered Locus Names:AHA_3017
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length326 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate By similarity. SAAS SAAS006203

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. SAAS SAAS006203

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. SAAS SAAS006203

Subcellular location

Cytoplasm By similarity SAAS SAAS006203.

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Sequences

Sequence LengthMass (Da)Tools
A0KMM0 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 175492C9BC12007C

FASTA32634,593
        10         20         30         40         50         60 
MSSDMYQSSS VVAYAPASSA NLSVGFDVLG AALAPVDGSL LGDRVQVKAA DVPFALSSVG 

        70         80         90        100        110        120 
RYAHKLPADP KKNILHDCWL AYGEALEKRG LGLKPLEMVL EKNLPVGSGL GSSACSVVAA 

       130        140        150        160        170        180 
LEGLNAFHGA PLNEHDLLLL MGEMEGKISG SVHYDNVAPC YLGGMQLVLE EHGVISQGIP 

       190        200        210        220        230        240 
VFEQWYWVVC YPGTVVSTAA ARAILPAQYR RQDCLTYGRR LAAFVHASYT GQEGLAASVL 

       250        260        270        280        290        300 
KDVIAEPYRS ALIEGFAEVR AQAAQNGALA TGISGSGPSV FVVMKDLAQA ERMKDWMDAH 

       310        320 
FVQNEDGFAR VCKLDMAGAR VTGSEL

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed: 16980456] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000462 Genomic DNA. Translation: ABK38756.1.
RefSeqYP_857521.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KMM0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0KMM0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4489042.
GenomeReviewsGene locus AHA_3017 in contig CP000462_GR.
KEGGaha:AHA_3017.
PATRIC20783648. VBIAerHyd135212_3020.
TIGRAHA_3017.

Phylogenomic databases

eggNOGCOG0083.
HOGENOMHBG646290.
OMAGSAHADN.
PhylomeDBA0KMM0.
ProtClustDBPRK01212.

Family and domain databases

InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR000870. Homoserine_kinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00872.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000676. Homoser_kin. 1 hit.
PRINTSPR00958. HOMSERKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00191. ThrB. 1 hit.
PROSITEPS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0KMM0_AERHH
AccessionPrimary (citable) accession number: A0KMM0
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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