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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:AHA_2983
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000756 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000595011 – 642Chaperone protein DnaKAdd BLAST642

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei199Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA0KMI6.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi380703.AHA_2983.

Structurei

3D structure databases

ProteinModelPortaliA0KMI6.
SMRiA0KMI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiISIKRHM.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiView protein in InterPro
IPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0KMI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAILD GDHARVIENA EGDRTTPSII AYADDGEILV
60 70 80 90 100
GQPAKRQAIT NPKNTLFAIK RLIGRRFEDD EVQRDLEIMP YAIAKADNGD
110 120 130 140 150
AWVEVKGKKM APPQISAEVL KKMKKTAEDY LGEPVTEAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGRI AGLDVKRIIN EPTAAAFAYG VNKVKGERKV AVYDLGGGTF
210 220 230 240 250
DISIIEIDEV EGETTFEVLA TNGNTHLGGE DFDNRVINYL VEEFKREQGI
260 270 280 290 300
DLRKDQLALQ RLKDAAEKAK IELSSAQQTD VNLPYITADA TGPKHMNIKV
310 320 330 340 350
TRAKLESLVE DMVKDSLEPV RVALKDSGLA VGEIDDVILV GGQTRMPMVQ
360 370 380 390 400
KAVADFFGKE PRKDVNPDEA VAMGAAIQGA VLSGDKTDVL LLDVTPLSLG
410 420 430 440 450
IETMGSVMTA LIEKNTTIPT KKSQVFSTAE DNQSAVTIHV LQGERKRASD
460 470 480 490 500
NKSLGQFNLE GIRPAPRGLP QIEVTFDIDA NGILHVSAKD KETNKEQKIT
510 520 530 540 550
IQASSGLSDD EIERMVREAE ANAAEDKKFE ELVQTRNQAD GLVHSVRKQI
560 570 580 590 600
TEAGEALPAD DKTKIEAALS ELESAIKGDD KAAIEAKQQA LLEASQKLME
610 620 630 640
IAQQQAQAQG AAGADAGQSS SSAKADDDVV DAEFEEVKDD KK
Length:642
Mass (Da):69,429
Last modified:December 12, 2006 - v1
Checksum:i698CD116578BE646
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA. Translation: ABK38561.1.
RefSeqiWP_011706781.1. NC_008570.1.
YP_857487.1. NC_008570.1.

Genome annotation databases

EnsemblBacteriaiABK38561; ABK38561; AHA_2983.
GeneIDi4488919.
KEGGiaha:AHA_2983.
PATRICifig|380703.7.peg.2982.

Similar proteinsi

Entry informationi

Entry nameiDNAK_AERHH
AccessioniPrimary (citable) accession number: A0KMI6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 12, 2006
Last modified: June 7, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families