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A0KKU5 (A0KKU5_AERHH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def-2 EMBL ABK39499.1
Synonyms:def2 HAMAP MF_00163
Ordered Locus Names:AHA_2373
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1341 By similarity HAMAP MF_00163
Metal binding911Iron By similarity HAMAP MF_00163
Metal binding1331Iron By similarity HAMAP MF_00163
Metal binding1371Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A0KKU5 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 65A7DA5C188EF35F

FASTA16618,149
        10         20         30         40         50         60 
MAMLDILTVP DPRLGIKAEQ VEDIAAVQGL IDDMLETLYA TDNGIGLAAT QVGRKEAIVI 

        70         80         90        100        110        120 
IDLSEKRDQP LVLINPQVTS GTEPALGQEG CLSVPDYYAD VERYGSVVVS ALDRHGVPIT 

       130        140        150        160 
VKSSDFLAIV MQHEIDHLQG KVFIDYLSPL KRKMALKKVK KHLKAT

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed: 16980456] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000462 Genomic DNA. Translation: ABK39499.1.
RefSeqYP_856896.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KKU5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0KKU5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4490347.
GenomeReviewsGene locus AHA_2373 in contig CP000462_GR.
KEGGaha:AHA_2373.
PATRIC20782320. VBIAerHyd135212_2375.
TIGRAHA_2373.

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAMINAHIE.
PhylomeDBA0KKU5.
ProtClustDBPRK12846.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0KKU5_AERHH
AccessionPrimary (citable) accession number: A0KKU5
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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