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Protein

Monofunctional biosynthetic peptidoglycan transglycosylase

Gene

mtgA

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cell wall formation.UniRule annotation

Pathway: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciAHYD380703:GH2M-2130-MONOMER.
UniPathwayiUPA00219.

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Names & Taxonomyi

Protein namesi
Recommended name:
Monofunctional biosynthetic peptidoglycan transglycosylaseUniRule annotation (EC:2.4.2.-UniRule annotation)
Short name:
Monofunctional TGaseUniRule annotation
Gene namesi
Name:mtgAUniRule annotation
Ordered Locus Names:AHA_2130
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000756 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3423HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Monofunctional biosynthetic peptidoglycan transglycosylasePRO_1000017298Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi380703.AHA_2130.

Structurei

3D structure databases

ProteinModelPortaliA0KK53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 51 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0744.
HOGENOMiHOG000288117.
KOiK03814.
OMAiQIALWSF.
OrthoDBiEOG6HMXCD.

Family and domain databases

HAMAPiMF_00766. Mono_pep_trsgly.
InterProiIPR001264. Glyco_trans_51.
IPR023346. Lysozyme-like_dom.
IPR011812. Mono_pep_trsgly.
[Graphical view]
PfamiPF00912. Transgly. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
TIGRFAMsiTIGR02070. mono_pep_trsgly. 1 hit.

Sequencei

Sequence statusi: Complete.

A0KK53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPALARRLL SGLGKLLLAA LLSTIVSVAL LRFIDPPMWT WRLERALFPP
60 70 80 90 100
AKVAEVKHDW VPLEQISREL QLAVIAAEDQ RFAEHNGFDM DAISSALKHN
110 120 130 140 150
QHSERVRGAS TLSQQTAKNL FMWSDRSFLR KGIEAWFTLL MELGWDKSRI
160 170 180 190 200
LEMYLNIVEF GPGIYGAEAA ARHYFGKPAA RLTRYEASLL AAALPNPWRY
210 220 230
RVKPPSPYVQ QRSAWIRRQM GQLGQITLNK VHQAD
Length:235
Mass (Da):26,801
Last modified:December 12, 2006 - v1
Checksum:iF0F77935E173BE47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA. Translation: ABK38359.1.
RefSeqiWP_011705989.1. NC_008570.1.
YP_856654.1. NC_008570.1.

Genome annotation databases

EnsemblBacteriaiABK38359; ABK38359; AHA_2130.
GeneIDi4487631.
KEGGiaha:AHA_2130.
PATRICi20781832. VBIAerHyd135212_2131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA. Translation: ABK38359.1.
RefSeqiWP_011705989.1. NC_008570.1.
YP_856654.1. NC_008570.1.

3D structure databases

ProteinModelPortaliA0KK53.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi380703.AHA_2130.

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK38359; ABK38359; AHA_2130.
GeneIDi4487631.
KEGGiaha:AHA_2130.
PATRICi20781832. VBIAerHyd135212_2131.

Phylogenomic databases

eggNOGiCOG0744.
HOGENOMiHOG000288117.
KOiK03814.
OMAiQIALWSF.
OrthoDBiEOG6HMXCD.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciAHYD380703:GH2M-2130-MONOMER.

Family and domain databases

HAMAPiMF_00766. Mono_pep_trsgly.
InterProiIPR001264. Glyco_trans_51.
IPR023346. Lysozyme-like_dom.
IPR011812. Mono_pep_trsgly.
[Graphical view]
PfamiPF00912. Transgly. 1 hit.
[Graphical view]
SUPFAMiSSF53955. SSF53955. 1 hit.
TIGRFAMsiTIGR02070. mono_pep_trsgly. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240.

Entry informationi

Entry nameiMTGA_AERHH
AccessioniPrimary (citable) accession number: A0KK53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: May 27, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.