SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0KJM0

- PHNX_AERHH

UniProt

A0KJM0 - PHNX_AERHH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphonoacetaldehyde hydrolase
Gene
phnX, AHA_1940
Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in phosphonate degradation By similarity.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei20 – 201Nucleophile By similarity
Metal bindingi20 – 201Magnesium By similarity
Metal bindingi22 – 221Magnesium; via carbonyl oxygen By similarity
Active sitei62 – 621Schiff-base intermediate with substrate By similarity
Metal bindingi196 – 1961Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciAHYD380703:GH2M-1940-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
Short name:
Phosphonatase
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene namesi
Name:phnX
Ordered Locus Names:AHA_1940
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
ProteomesiUP000000756: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Phosphonoacetaldehyde hydrolaseUniRule annotation
PRO_0000284573Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi380703.AHA_1940.

Structurei

3D structure databases

ProteinModelPortaliA0KJM0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000217971.
KOiK05306.
OMAiGATWEEY.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

A0KJM0-1 [UniParc]FASTAAdd to Basket

« Hide

MTDLQIAVDP TTDVEALILD WAGTVVDFGS FAPTSIFVEA FARAYDFPVT    50
LDEARQPMGL GKWDHIAALG RLPSVDARWQ ARFGHPMSHA EVDHLYHTFM 100
PLQIAAVTRF ADPIPGVLPV LDALRGQGMK IGSCSGYPRP VMETLVPAAA 150
DHGYRPDHWV ATDDLKAGGR PGPWMALANV IELGVNAVHR CIKVDDAVPG 200
ISEGLNAGMW TVGLSVSGNE FGATWEAFAA MSEAEIAARR APAEAKLRAA 250
GAHYVIDTLA DIAPVIADIN RRLAAGERP 279
Length:279
Mass (Da):29,882
Last modified:December 12, 2006 - v1
Checksum:i5599F76509E3D2AF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000462 Genomic DNA. Translation: ABK38391.1.
RefSeqiWP_011705810.1. NC_008570.1.
YP_856471.1. NC_008570.1.

Genome annotation databases

EnsemblBacteriaiABK38391; ABK38391; AHA_1940.
GeneIDi4489099.
KEGGiaha:AHA_1940.
PATRICi20781468. VBIAerHyd135212_1955.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000462 Genomic DNA. Translation: ABK38391.1 .
RefSeqi WP_011705810.1. NC_008570.1.
YP_856471.1. NC_008570.1.

3D structure databases

ProteinModelPortali A0KJM0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 380703.AHA_1940.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK38391 ; ABK38391 ; AHA_1940 .
GeneIDi 4489099.
KEGGi aha:AHA_1940.
PATRICi 20781468. VBIAerHyd135212_1955.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000217971.
KOi K05306.
OMAi GATWEEY.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci AHYD380703:GH2M-1940-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 7966 / NCIB 9240.

Entry informationi

Entry nameiPHNX_AERHH
AccessioniPrimary (citable) accession number: A0KJM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: December 12, 2006
Last modified: September 3, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi