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Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HscA homologUniRule annotation
Gene namesi
Name:hscAUniRule annotation
Ordered Locus Names:AHA_1751
OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Taxonomic identifieri380703 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
Proteomesi
  • UP000000756 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000448401 – 615Chaperone protein HscA homologAdd BLAST615

Interactioni

Protein-protein interaction databases

STRINGi380703.AHA_1751.

Structurei

3D structure databases

ProteinModelPortaliA0KJ36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9I. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0KJ36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLQIAEPG QSAAPHQHKR AVGIDLGTTN SLVAAVRSGQ ADTLCDEQGR
60 70 80 90 100
DLLPSVVHYQ ADTIRVGVDA KREAALDPHN TIVSAKRMMG KALADIDTRQ
110 120 130 140 150
QPYQFVAADN GMPQLQTRQG LVNPVQVSAE ILKKLAERGA AALGGDLDGV
160 170 180 190 200
VITVPAYFDD AQRQGTKDAA RLAGLHVLRL LNEPTAAAIA YGLDSGQEGV
210 220 230 240 250
IAVYDLGGGT FDISILRLHR GVFEVMATGG DSALGGDDFD HLLADWLKEQ
260 270 280 290 300
AGLTGELDAR LQRELLDVAA AVKHGLTDAD AVPCTFAGWQ GSVTRSQFDE
310 320 330 340 350
LIQPLVKRTL LACRRALRDA GLEQEEVLEV VMVGGSTRVP LVRELVGEFF
360 370 380 390 400
QRPPLTSIDP DKVVAIGAAI QADILVGNKP DAEMLLLDVI PLSLGLETMG
410 420 430 440 450
GLAEKVIPRN TTIPVARAQE FTTFKDGQTA MAIHVVQGER ELVADCRSLA
460 470 480 490 500
RFTLTGIPPM VAGAAHIRVT FQVDADGLLS VSAMEKSSGV QAEIQVKPSY
510 520 530 540 550
GLGEDDILNM LSASIANAQQ DMDARMLAEQ QVEADRVVES LNAALAADGE
560 570 580 590 600
ALLSPAERAE LDAAIAHLLT MRSTGTTNQI KEAIEAADAA SGEFAARRMD
610
ASIRKVLTGQ NVNKV
Length:615
Mass (Da):65,304
Last modified:December 12, 2006 - v1
Checksum:i46DCBB32A9362B15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA. Translation: ABK37680.1.
RefSeqiWP_011705638.1. NC_008570.1.
YP_856287.1. NC_008570.1.

Genome annotation databases

EnsemblBacteriaiABK37680; ABK37680; AHA_1751.
GeneIDi4490281.
KEGGiaha:AHA_1751.
PATRICi20781078. VBIAerHyd135212_1765.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA. Translation: ABK37680.1.
RefSeqiWP_011705638.1. NC_008570.1.
YP_856287.1. NC_008570.1.

3D structure databases

ProteinModelPortaliA0KJ36.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi380703.AHA_1751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK37680; ABK37680; AHA_1751.
GeneIDi4490281.
KEGGiaha:AHA_1751.
PATRICi20781078. VBIAerHyd135212_1765.

Phylogenomic databases

eggNOGiENOG4105C9I. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSCA_AERHH
AccessioniPrimary (citable) accession number: A0KJ36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.