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A0KH11 (A0KH11_AERHH) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 1 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr-1 EMBL ABK36160.1
Synonyms:alr1 HAMAP MF_01201
Ordered Locus Names:AHA_1015
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2541Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
A0KH11 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 8C552F85D7AF5CD9

FASTA35738,774
        10         20         30         40         50         60 
MKAAIAQINT AALRHNLAVV KRHAPQCKII AVVKANAYGH GLLPVARTLV DADAYAVARI 

        70         80         90        100        110        120 
EEALMLRSCA VVKPIVLLEG FFSAADLPVL AANNLQTAVH TWEQLEALEQ ADLPAPVVAW 

       130        140        150        160        170        180 
LKLDTGMHRL GVRADEMPAF IERLAKCKNV VQPFNIMTHF SRSDELEQPT TREQIDLFSQ 

       190        200        210        220        230        240 
LTAPLLGERA MANSAGILAW PDSHCDWVRP GVILYGVSPF PNTVAADYDL QPVMTLKTQL 

       250        260        270        280        290        300 
IAVRDHKAGE PVGYGANWVS DRDTRLGVIA IGYGDGYPRM APNGTPVLVN GRIVPLVGRV 

       310        320        330        340        350 
SMDMTTVDLG PGATDKAGDE AVLWGEGLPV ERVADQIGTI PYELITKLTS RVFMEYV

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed: 16980456] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000462 Genomic DNA. Translation: ABK36160.1.
RefSeqYP_855561.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KH11.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0KH11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4488780.
GenomeReviewsGene locus AHA_1015 in contig CP000462_GR.
KEGGaha:AHA_1015.
PATRIC20779568. VBIAerHyd135212_1019.
TIGRAHA_1015.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHBG712172.
OMAEGTPVWV.
PhylomeDBA0KH11.
ProtClustDBCLSK728716.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0KH11_AERHH
AccessionPrimary (citable) accession number: A0KH11
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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