ID   A0KGX3_AERHH            Unreviewed;       869 AA.
AC   A0KGX3;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Chitinase A {ECO:0000313|EMBL:ABK39408.1};
DE            EC=3.2.1.14 {ECO:0000313|EMBL:ABK39408.1};
GN   OrderedLocusNames=AHA_0977 {ECO:0000313|EMBL:ABK39408.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39408.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK39408.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC   KCTC 2358 / NCIMB 9240 / NCTC 8049
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC       class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
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DR   EMBL; CP000462; ABK39408.1; -; Genomic_DNA.
DR   RefSeq; WP_011704912.1; NC_008570.1.
DR   RefSeq; YP_855521.1; NC_008570.1.
DR   AlphaFoldDB; A0KGX3; -.
DR   SMR; A0KGX3; -.
DR   STRING; 380703.AHA_0977; -.
DR   CAZy; CBM5; Carbohydrate-Binding Module Family 5.
DR   CAZy; GH18; Glycoside Hydrolase Family 18.
DR   EnsemblBacteria; ABK39408; ABK39408; AHA_0977.
DR   KEGG; aha:AHA_0977; -.
DR   PATRIC; fig|380703.7.peg.981; -.
DR   eggNOG; COG3325; Bacteria.
DR   eggNOG; COG3979; Bacteria.
DR   HOGENOM; CLU_002833_14_0_6; -.
DR   OrthoDB; 9775889at2; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd12215; ChiC_BD; 2.
DR   CDD; cd02848; E_set_Chitinase_N; 1.
DR   CDD; cd06548; GH18_chitinase; 1.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 2.10.10.20; Carbohydrate-binding module superfamily 5/12; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR003610; CBM_fam5/12.
DR   InterPro; IPR036573; CBM_sf_5/12.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR013540; ChitinaseA_N.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR   Pfam; PF02839; CBM_5_12; 2.
DR   Pfam; PF08329; ChitinaseA_N; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00495; ChtBD3; 2.
DR   SMART; SM00636; Glyco_18; 1.
DR   SMART; SM00089; PKD; 2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51055; Carbohydrate binding domain; 2.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   PROSITE; PS01095; GH18_1; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326};
KW   Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..869
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002625200"
FT   DOMAIN          158..564
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
SQ   SEQUENCE   869 AA;  92647 MW;  EA6B767802787249 CRC64;
     MLSPKPSVLA LLVGGLCASS AFAAAPGKPT IGWGETKFAI VEVDQAATSY NKLVKVHADG
     APVSVSWNLW SGDVGQTAKV LLDGKEVWSG AASASGTANF KVTKGGRYQM QVALCNADGC
     TLSDKKEILV ADTDGSHLLP LKAPLKENNK PYVNKTGKVM GAYYVEWGVY GRKFTVDKIP
     AQNLTHILYG FTPICGGNGI NDSLKEISGS FEALQRSCAG REDFKVSIHD PWAAIQMGQG
     NLTAYDEPYK GNFGNLMALK KAYPDLKILP SIGGWTLSDP FFFFGDKTKR DTFVASVKEY
     LQTWKFFDGV DIDWEFPGGL GANPNLGSAS DGETYVLLMK ELRAMLDELS AETGRTYELT
     SAISAGGDKI AKVDYRAAQQ YMNHIFLMSY DFNGAWTNTG LGHQTALYES SWDPNTKYTT
     DKGVKALLGQ GVEPGKVVVG AAMYGRGWTG VSGYQGNNPF TGTATGPIAG TEAEGIWEKG
     VIDYRGIAKG KMAGDWQYSY DEVAEAPSVF KAATGELITF DDERSVKAKG QYVLANQLGG
     LFAWEIDADN GDILNAMHEG LGHGDSTPPV NKPPVANAGT DLAVTGPAQL VLDGSSSRDP
     EGAVLSYSWA QISGPKATLS DATQAKAKVS VDAVSQDVNL VFELTVTDDH NLSAKDQVVV
     TNKAPQPNLP PVVTVQDKVS VQAGKQVSIT ASATDPNGDT LSYQWSVPAG LTASGQNSKT
     LVVTGPSVAV ETGYDLTVTV TDGALDAQGK TRLTVTPVSG GGDCNATDPD AANWPAWKAS
     TTYNGGEKVS HNQLVWQAKY WTQGNEPSRT ADQWKLISQV QLGWDAGVAY NAGDVTTHNG
     RQWKAQYWTR GNEPGKHDVW QDIGAASCK
//