ID   SURE_AERHH              Reviewed;         253 AA.
AC   A0KGH8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=5'-nucleotidase surE;
DE            EC=3.1.3.5;
DE   AltName: Full=Nucleoside 5'-monophosphate phosphohydrolase;
GN   Name=surE; OrderedLocusNames=AHA_0826;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Nucleotidase that shows phosphatase activity on
CC       nucleoside 5'-monophosphates (By similarity).
CC   -!- CATALYTIC ACTIVITY: A 5'-ribonucleotide + H(2)O = a ribonucleoside
CC       + phosphate.
CC   -!- COFACTOR: Binds 1 divalent metal cation per subunit (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the surE nucleotidase family.
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DR   EMBL; CP000462; ABK39784.1; -; Genomic_DNA.
DR   RefSeq; YP_855369.1; -.
DR   GeneID; 4489306; -.
DR   GenomeReviews; CP000462_GR; AHA_0826.
DR   KEGG; aha:AHA_0826; -.
DR   TIGR; AHA_0826; -.
DR   OMA; A0KGH8; NLNIPPC.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008253; F:5'-nucleotidase activity; IEA:HAMAP.
DR   GO; GO:0046872; F:metal ion binding; IEA:HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   HAMAP; MF_00060; -; 1.
DR   InterPro; IPR002828; SurE-like_Pase/nucleotidase.
DR   Gene3D; G3DSA:3.40.1210.10; SurE-like_Pase/nucleotidase; 1.
DR   Pfam; PF01975; SurE; 1.
DR   ProDom; PD005378; SurE; 1.
DR   TIGRFAMs; TIGR00087; surE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Hydrolase; Metal-binding;
KW   Nucleotide-binding.
FT   CHAIN         1    253       5'-nucleotidase surE.
FT                                /FTId=PRO_1000007699.
FT   METAL         8      8       Divalent metal cation (By similarity).
FT   METAL         9      9       Divalent metal cation (By similarity).
FT   METAL        39     39       Divalent metal cation (By similarity).
FT   METAL        97     97       Divalent metal cation (By similarity).
SQ   SEQUENCE   253 AA;  26677 MW;  956A5E152F31360B CRC64;
     MRILVSNDDG VHAEGIRALS EALTACGEVI VVAPDRNRSG ASHSLTLEVP LRVTRLGETG
     FNGSESYAVK GTPTDCVHLA VNELVRPEPD MVVAGINHGA NLGDDVIYSG TVAAATEGRH
     LGFPSLAISL VGKTHFATAA HYAAQLVKGM MVHPLPADQI LNVNVPDLPL DQIKGIRVTR
     LGNRHRAESV ICSEDPRGQP IYWIGPPGSQ QDAGEGTDFA AIEQGYVSIT PLTIDMTAYS
     SLAGLGAWLD LQG
//