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A0KFU8 (CAPP_AERHH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:AHA_0591
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas ›

Protein attributes

Sequence length877 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the PEPCase type 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 877877Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025544

Sites

Active site1381 By similarity
Active site5431 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0KFU8 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 6EF0B3ECC2774D19

FASTA87799,020
        10         20         30         40         50         60 
MNEKYAALRA NVGMLGQLLG KSIKDHQGQA FLDKIETIRQ LAKSSRKGNE TDRERLLDTL 

        70         80         90        100        110        120 
RNLSDDELLP VARAFSQFLN LANVAEQFHT ISRRCEEQVC TPDPLEQMFD KLKASNLSQE 

       130        140        150        160        170        180 
AIIQAVRELD IDLVLTAHPT EVTRRTLIHK HVQLNDCLEA LELSDLLPRE RDKILNRIEQ 

       190        200        210        220        230        240 
LVNQAWHTNE IREQRPTPVD EAKWGFAVVE NSLWPAIPEF MRNLDERLQH HLGVRLPLDA 

       250        260        270        280        290        300 
APVKFTSWMG GDRDGNPFVT AKVTAEVLEL GRWMAVSLFY KDIKELTSEL SMSDCTDAVR 

       310        320        330        340        350        360 
ERVGDHPEPY RALVRELREQ LRETQEFLTA KVQGQASESR DLVKTTAQLR EPLELCYHSL 

       370        380        390        400        410        420 
HACGMGNIAD GMLLDVLRKL ACFGIHLVKL DIRQDGERHG QVFSELTRYL GMGDYAEWSE 

       430        440        450        460        470        480 
DDKQAFLLNE LNSRRPLIPT DWEPSDETRE TLDTCKVIAQ HDPDAFGIYI ISMAGAPSDV 

       490        500        510        520        530        540 
LAVQLLLKEA GCKFRMPVAP LFETQEDLMA GTAVMERLLS VDWYRGYIQG RQYVMIGYSD 

       550        560        570        580        590        600 
SAKDAGMMAA GWAQYAAMES LVALAEANNL RLTLFHGRGG TVGRGGAPAH QAILSQPPGS 

       610        620        630        640        650        660 
LRGGLRVTEQ GEMIRFKFGL PKVAIQSLNL YTSAVLEGNL LPPPKPKECW RAVMEQLASV 

       670        680        690        700        710        720 
SCDHYRSIVR GHPDFVPYFR AATPEMELGK LPLGSRPSKR KPNGGVESLR AIPWIFAWTQ 

       730        740        750        760        770        780 
NRLMLPAWLG AHKGLQQAIA DGQKGVLEEM SRQWPFFRTR LEMLEMVFLK ADVWLAEYYD 

       790        800        810        820        830        840 
TRLVPKELWG LGKQLRQELA DSIQVVLELR PQGDLLDDQP WIKESIKLRN PYTDPLNVLQ 

       850        860        870 
VELLGRSRNH AETLHPELDQ ALMVTIAGIA AGMRNTG

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 7966 / NCIB 9240.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000462 Genomic DNA. Translation: ABK39687.1.
RefSeqYP_855124.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KFU8.
SMRA0KFU8. Positions 4-877.
ModBaseSearch...

Protein-protein interaction databases

STRING380703.AHA_0591.

Proteomic databases

PRIDEA0KFU8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK39687; ABK39687; AHA_0591.
GeneID4489258.
KEGGaha:AHA_0591.
PATRIC20778684. VBIAerHyd135212_0587.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycAHYD380703:GH2M-727-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_AERHH
AccessionPrimary (citable) accession number: A0KFU8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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