ID   UBIC_AERHH              Reviewed;         178 AA.
AC   A0KEP8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   16-JUN-2009, entry version 17.
DE   RecName: Full=Probable chorismate--pyruvate lyase;
DE            Short=CL;
DE            Short=CPL;
DE            EC=4.1.3.40;
GN   Name=ubiC; OrderedLocusNames=AHA_0180;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Removes the pyruvyl group from chorismate, with
CC       concomitant aromatization of the ring, to provide 4-
CC       hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity).
CC   -!- CATALYTIC ACTIVITY: Chorismate = 4-hydroxybenzoate + pyruvate.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the ubiC family.
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DR   EMBL; CP000462; ABK37637.1; -; Genomic_DNA.
DR   RefSeq; YP_854713.1; -.
DR   GeneID; 4486810; -.
DR   GenomeReviews; CP000462_GR; AHA_0180.
DR   KEGG; aha:AHA_0180; -.
DR   TIGR; AHA_0180; -.
DR   OMA; A0KEP8; LQITHTH.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008813; F:chorismate lyase activity; IEA:HAMAP.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_01632; -; 1.
DR   InterPro; IPR007440; Chorismate_lyase.
DR   Pfam; PF04345; Chor_lyase; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Pyruvate;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    178       Probable chorismate--pyruvate lyase.
FT                                /FTId=PRO_1000069740.
FT   BINDING      37     37       Substrate; via amide nitrogen (By
FT                                similarity).
FT   BINDING      78     78       Substrate (By similarity).
FT   BINDING     114    114       Substrate; via amide nitrogen (By
FT                                similarity).
SQ   SEQUENCE   178 AA;  20132 MW;  7BD810730997C01E CRC64;
     MKSELTVPLA RLVPWQTPAQ CEPPEALLPW LLEADSMTRR LRRHNRHFSV QLFGNRSVAL
     DADEQQLVVA EQPMGLCREV ILHGDHGPAV LGWTLFAEAA LQESGLRELG EQPLGERIFG
     DEPARRDHLQ LACFEIASNP WCPAGTVWGR RSRLFLGQWP LLVHELFLPS LSCNKELE
//