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A0KEM2 (G6PI_AERHH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:AHA_0154
OrganismAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) [Complete proteome] [HAMAP]
Taxonomic identifier380703 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013937

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0KEM2 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 4B92705D5DBBA948

FASTA54961,277
        10         20         30         40         50         60 
MKNINPTQTQ AWQALEAHFA ANKETRLKDL FAQDPKRFDK FSLTFGGDIL VDYSKNLITE 

        70         80         90        100        110        120 
ETLKLLVDLA KETDLRSAID AMFNGDKINM TEGRSVLHVA LRNRSDRPIE CDGKDVMPEV 

       130        140        150        160        170        180 
NAVLAKMKGF CEKIISGEWK GYTGKAIQHV VNIGIGGSDL GPVMITEALR PYKNHLQMHF 

       190        200        210        220        230        240 
VSNVDGTHIA ETLKKIDPET TLFLVASKTF TTQETMTNAL TARDWFIKIA GDKAHVAKHF 

       250        260        270        280        290        300 
AALSTNGKAV AEFGIDTNNM FEFWDWVGGR YSSWSAIGMP IALSVGFENF EALLQGAFEM 

       310        320        330        340        350        360 
DMHFATASYE QNVPVLLALI GLWYNNFYGA ESEAILPYDQ YMHRFPAYFQ QGNMESNGKY 

       370        380        390        400        410        420 
VDRNGKPVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLIP CDFLAPAISH NPIGDHHPKL 

       430        440        450        460        470        480 
LANFFAQTEA LAFGKSKEQV EAEFLAAGKT LEQVKDLVPF KVFEGNRPTN SILFKSLTPK 

       490        500        510        520        530        540 
TLGALIAMYE HKIFVQGAIW NIFSFDQWGV ELGKQLANKI LPELNTDAAV TSHDCSTNGL 


INTWKAWKA 

« Hide

References

[1]"Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades."
Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.
J. Bacteriol. 188:8272-8282(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 7966 / NCIB 9240.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000462 Genomic DNA. Translation: ABK39217.1.
RefSeqYP_854687.1. NC_008570.1.

3D structure databases

ProteinModelPortalA0KEM2.
SMRA0KEM2. Positions 10-542.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING380703.AHA_0154.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK39217; ABK39217; AHA_0154.
GeneID4490335.
KEGGaha:AHA_0154.
PATRIC20777774. VBIAerHyd135212_0144.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycAHYD380703:GH2M-154-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_AERHH
AccessionPrimary (citable) accession number: A0KEM2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways