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A0KEJ0

- NORR_AERHH

UniProt

A0KEJ0 - NORR_AERHH

Protein

Anaerobic nitric oxide reductase transcription regulator NorR

Gene

norR

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi214 – 2218ATPUniRule annotation
    Nucleotide bindingi277 – 28610ATPUniRule annotation
    DNA bindingi483 – 50220H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: UniProtKB-KW
    3. nucleoside-triphosphatase activity Source: InterPro
    4. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. phosphorelay signal transduction system Source: UniProtKB-HAMAP
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAHYD380703:GH2M-118-MONOMER.
    UniPathwayiUPA00638.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Anaerobic nitric oxide reductase transcription regulator NorRUniRule annotation
    Gene namesi
    Name:norRUniRule annotation
    Ordered Locus Names:AHA_0118
    OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240)
    Taxonomic identifieri380703 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
    ProteomesiUP000000756: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 508508Anaerobic nitric oxide reductase transcription regulator NorRPRO_0000305616Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei56 – 5614-aspartylphosphateUniRule annotation

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi380703.AHA_0118.

    Structurei

    3D structure databases

    ProteinModelPortaliA0KEJ0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini186 – 415230Sigma-54 factor interactionUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 sigma-54 factor interaction domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3604.
    HOGENOMiHOG000058487.
    KOiK12266.
    OMAiHSCIGLP.
    OrthoDBiEOG6WHNMG.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    3.30.450.40. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01314. NorR.
    InterProiIPR003593. AAA+_ATPase.
    IPR003018. GAF.
    IPR029016. GAF_dom_like.
    IPR009057. Homeodomain-like.
    IPR023944. NorR.
    IPR027417. P-loop_NTPase.
    IPR002078. Sigma_54_int.
    IPR025662. Sigma_54_int_dom_ATP-bd_1.
    IPR025944. Sigma_54_int_dom_CS.
    [Graphical view]
    PfamiPF01590. GAF. 1 hit.
    PF00158. Sigma54_activat. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00065. GAF. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF55781. SSF55781. 1 hit.
    PROSITEiPS00675. SIGMA54_INTERACT_1. 1 hit.
    PS00688. SIGMA54_INTERACT_3. 1 hit.
    PS50045. SIGMA54_INTERACT_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0KEJ0-1 [UniParc]FASTAAdd to Basket

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    MISTDSLARI ALDLQLGISH QDRFHRLIQS VRSLLNSDAS ALLRYEGGQF    50
    IPLAIDGLMQ DVLGRRFALK DHPRMEAIAR AGDVVRFPAD SSLPDPYDGL 100
    LPDHDDFKVH ACVGLPLFSD QALIGALTID GMNPTQFDAI SDEELRLVGA 150
    LAAAALNNAL LLERLARQSS EPLVPGTRPG PEQPEMIGQS PAMARLRHEI 200
    EVVANSELNV LILGETGVGK ELIAKAVHRG SQRAKAPLVY LNCAALPESV 250
    AESELFGHVK GAFTGAIHNR AGKFELADQG TLFLDEIGEL SLPLQAKLLR 300
    VLQYGDLQRI GDDTPLKVNV RILAATNRDL KQAVVEGQFR ADLYHRLSVF 350
    PIHAPALRER PGDIPLLAGY FCERCRLSLG LEQLRIQPQA LQLLERHDWP 400
    GNVRELEHAI HRAAVLARAE QGSQTPTLAS HHFNLAAGPL PPSTSPAMAP 450
    MTPLPGGLGL RAATDAFQLA LIEQTLAAHN GNWAATARAL ELDSGNLHRL 500
    AKRLGLKA 508
    Length:508
    Mass (Da):55,065
    Last modified:December 12, 2006 - v1
    Checksum:iA53D06D5653CFFD9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000462 Genomic DNA. Translation: ABK35919.1.
    RefSeqiWP_011704146.1. NC_008570.1.
    YP_854649.1. NC_008570.1.

    Genome annotation databases

    EnsemblBacteriaiABK35919; ABK35919; AHA_0118.
    GeneIDi4487498.
    KEGGiaha:AHA_0118.
    PATRICi20777700. VBIAerHyd135212_0111.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000462 Genomic DNA. Translation: ABK35919.1 .
    RefSeqi WP_011704146.1. NC_008570.1.
    YP_854649.1. NC_008570.1.

    3D structure databases

    ProteinModelPortali A0KEJ0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 380703.AHA_0118.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK35919 ; ABK35919 ; AHA_0118 .
    GeneIDi 4487498.
    KEGGi aha:AHA_0118.
    PATRICi 20777700. VBIAerHyd135212_0111.

    Phylogenomic databases

    eggNOGi COG3604.
    HOGENOMi HOG000058487.
    KOi K12266.
    OMAi HSCIGLP.
    OrthoDBi EOG6WHNMG.

    Enzyme and pathway databases

    UniPathwayi UPA00638 .
    BioCyci AHYD380703:GH2M-118-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    3.30.450.40. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01314. NorR.
    InterProi IPR003593. AAA+_ATPase.
    IPR003018. GAF.
    IPR029016. GAF_dom_like.
    IPR009057. Homeodomain-like.
    IPR023944. NorR.
    IPR027417. P-loop_NTPase.
    IPR002078. Sigma_54_int.
    IPR025662. Sigma_54_int_dom_ATP-bd_1.
    IPR025944. Sigma_54_int_dom_CS.
    [Graphical view ]
    Pfami PF01590. GAF. 1 hit.
    PF00158. Sigma54_activat. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00065. GAF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF55781. SSF55781. 1 hit.
    PROSITEi PS00675. SIGMA54_INTERACT_1. 1 hit.
    PS00688. SIGMA54_INTERACT_3. 1 hit.
    PS50045. SIGMA54_INTERACT_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 7966 / NCIB 9240.

    Entry informationi

    Entry nameiNORR_AERHH
    AccessioniPrimary (citable) accession number: A0KEJ0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 2, 2007
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3