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Protein
Submitted name:

ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase module

Gene

Bcen2424_6483

Organism
Burkholderia cenocepacia (strain HI2424)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro
  3. DNA primase activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-6568-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase moduleImported
Gene namesi
Ordered Locus Names:Bcen2424_6483Imported
OrganismiBurkholderia cenocepacia (strain HI2424)Imported
Taxonomic identifieri331272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000000776 Componenti: Chromosome 3

Interactioni

Protein-protein interaction databases

STRINGi331272.Bcen2424_6483.

Structurei

3D structure databases

ProteinModelPortaliA0KDF0.
SMRiA0KDF0. Positions 645-932.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR002755. DNA_primase_S.
IPR014146. LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol_dom.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0KDF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKLDPYRR KRHFGATPEP EGAHGKRRAK PDTQAASKPK AKQPAARARH
60 70 80 90 100
PLRFVIQEHH ARRLHYDFRL ELDGTLKSWA VPKGPSFDPQ VKRLAVHVED
110 120 130 140 150
HPLEYASFEG EIPAGHYGAG SVVVWDEGTW TPDGGVAQAR EGYRAGKLTF
160 170 180 190 200
RLDGEKLHGG WALVRSGRQE GRQEQWLLIK ERDDDARSAD EFDVVGERPG
210 220 230 240 250
SVHDGAANGA ARKRAARRGR STDADGDVHD AQHASHESHE SHESHASHRP
260 270 280 290 300
TDPSQVEGAV RAPLPERVAP QLATLVDAPP TQGGWCYELK FDGYRILARI
310 320 330 340 350
AGKGARRRVT LMTREGRDWT AKLRAQRDAL AALDVDDAWL DGEAVVLGEN
360 370 380 390 400
GLPDFQALQN AFGTDRSDAI TFFVFDLPYL DGYDLRDASL NDRRALLEPL
410 420 430 440 450
LANSDPARVR FSPDLGEDVA SLIASACDTG LEGLIGKRAD SRYRAGRSPA
460 470 480 490 500
WIKLKCRRRQ EFVIGGFTEP SGSRHGFGAL LLGVHEPAPA GKRRRGPGPL
510 520 530 540 550
RYVGRVGTGF DARMLDRLAA ILRKHERDTM PFDEPPRERT RTRVHWVEPT
560 570 580 590 600
LVAECEFAEW TGDGIVRQAA FIALREDKPA AQIVREMPKH TETEVTMDQR
610 620 630 640 650
PTPHDDTRKR ASHAARESAD RKQSARSRAA ARAEDDASGP DTLGRVRITH
660 670 680 690 700
PERVLDPQSG TRKIDLARYW QWVAPWLLPD LEGRPVSLVR APGDIAGELF
710 720 730 740 750
FQKHAERREI PFVTQHEGLD PGHGPLLSID NVDALLGAAQ MGTVELHTWN
760 770 780 790 800
AHASNIERPD RIVFDLDPDP ALPWRTMIDA AQLVRGLLDE LGLVSFCKTS
810 820 830 840 850
GGKGLHVVVP LTRHAGWDDV KDFSRAVAQH VAGTLPDRFT ATMGPRHRRG
860 870 880 890 900
KIFVDYLRNG RGASTIAAYS VRARPGMGVS VPLDWDEVPD TTGGAQWTID
910 920 930
TLHERLDTLK RDPWEGYAKA RQRITAAMRA RLGADT
Length:936
Mass (Da):103,780
Last modified:December 12, 2006 - v1
Checksum:i890C89522B1D197C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000460 Genomic DNA. Translation: ABK13213.1.
RefSeqiWP_011695006.1. NC_008544.1.
YP_840106.1. NC_008544.1.

Genome annotation databases

EnsemblBacteriaiABK13213; ABK13213; Bcen2424_6483.
KEGGibch:Bcen2424_6483.
PATRICi19070693. VBIBurCen15205_6657.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000460 Genomic DNA. Translation: ABK13213.1.
RefSeqiWP_011695006.1. NC_008544.1.
YP_840106.1. NC_008544.1.

3D structure databases

ProteinModelPortaliA0KDF0.
SMRiA0KDF0. Positions 645-932.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi331272.Bcen2424_6483.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK13213; ABK13213; Bcen2424_6483.
KEGGibch:Bcen2424_6483.
PATRICi19070693. VBIBurCen15205_6657.

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-6568-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR002755. DNA_primase_S.
IPR014146. LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol_dom.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 3 of Burkholderia cenocepacia HI2424."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI2424Imported.

Entry informationi

Entry nameiA0KDF0_BURCH
AccessioniPrimary (citable) accession number: A0KDF0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: April 29, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.