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Protein

Aldose 1-epimerase

Gene

Bcen2424_6371

Organism
Burkholderia cenocepacia (strain HI2424)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathway: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-6456-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Ordered Locus Names:Bcen2424_6371Imported
OrganismiBurkholderia cenocepacia (strain HI2424)Imported
Taxonomic identifieri331272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000000776 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 PotentialImportedAdd
BLAST
Chaini30 – 387358 PotentialImportedPRO_5000165204Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA0KD40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG2017.
HOGENOMiHOG000072798.
KOiK01785.
OMAiNDVNSHA.
OrthoDBiEOG69WFM5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A0KD40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRRWPRQPM LVMGVFATFG LHAAVASAAP EVSISRADYG TTATGQAVSQ
60 70 80 90 100
YTLANRRGVT LKVITYGGIV TALDVPDRTG HAADIVLGFD SLRDYEAHNG
110 120 130 140 150
NIHFGALIGR YANRIAGGRF ALDGKTWKLP VNDGPNTLHG GPDSFDAKVW
160 170 180 190 200
TVTGTHSDAT GSSVTLRYVS PDGENGFPGT LTTDVTYTLT GDNQIRIDYR
210 220 230 240 250
ATTDKNTVVN LTNHSYFNLA GQAGGSVERQ LIEIAASRFT PTDDTSIPTG
260 270 280 290 300
QLASVAGTPM DLRQPTPIGA HLRDAYPQLA IAHGYDQNWV LDQGGQPAPA
310 320 330 340 350
FAARAYDPAS GRFLELYTTQ PGLQFYTANG LNGSVAGKGG TVYRQTDAFA
360 370 380
LEAEHFPDSP NHPAFPSTAL KPGETLHEVT VWRVGAR
Length:387
Mass (Da):41,376
Last modified:December 12, 2006 - v1
Checksum:i5B43777BE4A31DB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000460 Genomic DNA. Translation: ABK13103.1.
RefSeqiWP_011545656.1. NC_008544.1.
YP_839996.1. NC_008544.1.

Genome annotation databases

EnsemblBacteriaiABK13103; ABK13103; Bcen2424_6371.
KEGGibch:Bcen2424_6371.
PATRICi19070449. VBIBurCen15205_6535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000460 Genomic DNA. Translation: ABK13103.1.
RefSeqiWP_011545656.1. NC_008544.1.
YP_839996.1. NC_008544.1.

3D structure databases

ProteinModelPortaliA0KD40.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK13103; ABK13103; Bcen2424_6371.
KEGGibch:Bcen2424_6371.
PATRICi19070449. VBIBurCen15205_6535.

Phylogenomic databases

eggNOGiCOG2017.
HOGENOMiHOG000072798.
KOiK01785.
OMAiNDVNSHA.
OrthoDBiEOG69WFM5.

Enzyme and pathway databases

UniPathwayiUPA00242.
BioCyciBCEN331272:GHR7-6456-MONOMER.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 3 of Burkholderia cenocepacia HI2424."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI2424Imported.

Entry informationi

Entry nameiA0KD40_BURCH
AccessioniPrimary (citable) accession number: A0KD40
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: June 24, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.