Reviewed, UniProtKB/Swiss-Prot A0KCV5 (DEOC_BURCH)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	Bcen2424_6286

Organism

Burkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]

Taxonomic identifier

331272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 226	226	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_1000015310
Sites
	Active site	156	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	185	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0KCV5-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 887220CE40E78F49	FASTA	226	22,887
	10 20 30 40 50 60 MPLSNAQLAQ TIDHTLLAPD ASDAQIRELC RQAAEHRFYS VCVNSANVPL AARELAETGV 70 80 90 100 110 120 LVCAVVGFPL GAGLSAAKAF EATAAIAAGA GEIDMVINLG ALKSGRADDV KADIDAVHRA 130 140 150 160 170 180 CGTVPLKVIL ETGLLTDDEK VRVCEMCRDL GVAFVKTSTG FGHGGATLAD VALMRRTVGP 190 200 210 220 TLGVKASGGV RDRAAALAML EAGATRLGTS SGVAIVTDQG GGAAGY

References

[1]

"Complete sequence of chromosome 3 of Burkholderia cenocepacia HI2424." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000460 Genomic DNA. Translation: ABK13018.1.
RefSeq	YP_839911.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4454019.
GenomeReviews	Gene locus Bcen2424_6286 in contig CP000460_GR.
KEGG	bch:Bcen2424_6286.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	A0KCV5.
OMA	A0KCV5. AKMIDHT.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_BURCH

Accession

Primary (citable) accession number: A0KCV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	June 16, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)