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A0K9J9

- A0K9J9_BURCH

UniProt

A0K9J9 - A0K9J9_BURCH

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia cenocepacia (strain HI2424)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei219 – 2191UniRule annotation
Active sitei661 – 6611UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-2495-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Bcen2424_2426Imported
OrganismiBurkholderia cenocepacia (strain HI2424)Imported
Taxonomic identifieri331272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000000776: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi331272.Bcen2424_2426.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiSILNCET.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0K9J9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSSGSARTA RRNAALPSPD ASTDTVATAA NGRAKTATKP TATKPKDPIR
60 70 80 90 100
QTKRTTKATS PAARNAVAPK AGTRTRDDKD GPLFEDIRFL GRLLGDVVRE
110 120 130 140 150
QEGDTVFDVV ETIRQTAVKF RREDDSEAAQ TLEKKLRKLT PEQTVSVVRA
160 170 180 190 200
FSYFSHLANI AEDRHHNRRR RIHALAGSAP QPGTVAYALD QLKTTGNASK
210 220 230 240 250
RLLQRFFDDA LIVPVLTAHP TEVQRKSILD AQHDIARLLA ERDQELTARE
260 270 280 290 300
RQYNETMLRA RVTALWQTRM LRDARLTVGD EIENALSYYR ATFLDELPAL
310 320 330 340 350
YGDIEAALAE HGLSARVPAF FQMGSWIGGD RDGNPNVTAA TLDEAINRQA
360 370 380 390 400
AVILEHYLEQ VHKLGAELSV SNLLVGANDA VKALAAASPD QSPHRVDEPY
410 420 430 440 450
RRALIGIYTR LAASARVRLG EGTVPVRSAG RGAPPVRAIP YEDSEAFVAD
460 470 480 490 500
LKMLTASLDE HHGASLAAPR LAPLVRAAEV FGFHLASIDL RQSSDIHEAV
510 520 530 540 550
VAELFARAGV EADYAALAEE DKLRVLLAAL ADPRPLRSPY LEYSALAQSE
560 570 580 590 600
LGVFEKAREV RAQFGARAVR NYIISHTETV SDLVEVLLLQ KETGLLEGTL
610 620 630 640 650
GVPGSHAKNS LMVIPLFETI PDLRDASRIM RDYFALPGID ALIAHQGAEQ
660 670 680 690 700
EVMLGYSDSN KDGGFLTSNW ELYRAELALV DLFRERKITL RLFHGRGGTV
710 720 730 740 750
GRGGGPTYQA ILSQPPGTVN GQIRLTEQGE VIASKFSNPS IGRRNLETVV
760 770 780 790 800
AATLEASLLP QSNAPAQLPA FEAAMQTLSD SAMAAYRALV YETPGFTDYF
810 820 830 840 850
FSSTPITEIA ELNIGSRPAS RKLQDPKQRK IEDLRAIPWG FSWGQCRLLL
860 870 880 890 900
TGWYGFGSAV SAYLDGAQDD AERAKRVTLL KKMNKTWPFF ANLLSNMDMV
910 920 930 940 950
LAKTDLAVAS RYAQLVSDRK LRKHVFERIV AEWERTSRAL AEITGQEGRL
960 970 980 990 1000
ATNPLLARSI KNRFPYLDPL NHLQVELIKR HRAGDTNARL RRGIHLTING

IAAGLRNTG
Length:1,009
Mass (Da):110,956
Last modified:December 12, 2006 - v1
Checksum:iEF97B97F34A8DD3A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000458 Genomic DNA. Translation: ABK09176.1.
RefSeqiWP_011694359.1. NC_008542.1.
YP_836069.1. NC_008542.1.

Genome annotation databases

EnsemblBacteriaiABK09176; ABK09176; Bcen2424_2426.
GeneIDi4448322.
KEGGibch:Bcen2424_2426.
PATRICi19062268. VBIBurCen15205_2473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000458 Genomic DNA. Translation: ABK09176.1 .
RefSeqi WP_011694359.1. NC_008542.1.
YP_836069.1. NC_008542.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331272.Bcen2424_2426.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK09176 ; ABK09176 ; Bcen2424_2426 .
GeneIDi 4448322.
KEGGi bch:Bcen2424_2426.
PATRICi 19062268. VBIBurCen15205_2473.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi SILNCET.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci BCEN331272:GHR7-2495-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI2424Imported.

Entry informationi

Entry nameiA0K9J9_BURCH
AccessioniPrimary (citable) accession number: A0K9J9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3