A0K9A9 (TAL_BURCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Bcen2424_2335

Organism

Burkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]

Taxonomic identifier

331272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 317	317	Transaldolase HAMAP MF_00492		PRO_1000014488
Sites
	Active site	126	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0K9A9 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: EB13CE40B8D81871	FASTA	317	35,379
	10 20 30 40 50 60 MTTALDQLKQ YTTVVADTGD FQQLAQYKPQ DATTNPSLIL KAVQKDAYKP ILEKTVRDHR 70 80 90 100 110 120 NESTDFIIDR LLIAFGTEIL KLIPGRVSTE VDARLSFDTQ RSIEKGRELI KLYEAAGIGR 130 140 150 160 170 180 ERILIKLAST WEGIRAAEVL QKEGIKCNMT LLFSLVQAAA CAEAGAQLIS PFVGRIYDWY 190 200 210 220 230 240 KKQAGAEWNE ARDGGANDPG VQSVRRIYTY YKTFGYKTEV MGASFRTTSQ ITELAGCDLL 250 260 270 280 290 300 TISPDLLQKL QESNETVARK LSPETLQDKP AERVAIDEAS FRFQLNDEAM ATEKLAEGIR 310 VFAADAVKLE KLIDALR

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HI2424.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000458 Genomic DNA. Translation: ABK09086.1.
RefSeq	YP_835979.1. NC_008542.1.
3D structure databases
ProteinModelPortal	A0K9A9.
SMR	A0K9A9. Positions 1-315.
ModBase	Search...
Protein-protein interaction databases
STRING	A0K9A9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4450176.
GenomeReviews	Gene locus Bcen2424_2335 in contig CP000458_GR.
KEGG	bch:Bcen2424_2335.
PATRIC	19062087. VBIBurCen15205_2385.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HBG286747.
OMA	GCEILAI.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	BCEN331272:BCEN2424_2335-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_BURCH

Accession

Primary (citable) accession number: A0K9A9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program