Unreviewed, UniProtKB/TrEMBL A0K981 (A0K981_BURCH)

Names and origin

Protein names

Submitted name:
Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA EMBL ABK09058.1

Gene names

Ordered Locus Names:

Bcen2424_2307

Organism

Burkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]

Taxonomic identifier

331272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation By similarity. Spearmint SPM017940
Subunit structure	Homodimer By similarity. Spearmint SPM017940
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Lipid transport Spearmint SPM017940 Transport
Cellular component	Cell inner membrane Spearmint SPM017940 Cell membrane Membrane
Domain	Signal EMBL ABK09058.1 Transmembrane Spearmint SPM011917
Ligand	ATP-binding Spearmint SPM011917 RuleBase RU000684V4 Nucleotide-binding
Molecular function	Hydrolase Spearmint SPM017940
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid transport Inferred from electronic annotation. Source: UniProtKB-KW transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 38	38	Potential EMBL ABK09058.1
	Chain	39 – 583	545	Potential EMBL ABK09058.1		PRO_5000164938

Sequences

	Sequence		Length	Mass (Da)
	A0K981-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 1729BF51DB367AA1	FASTA	583	63,593
	10 20 30 40 50 60 MDGTGTSPMT VLKRLWPYIR PLIGIVVLAV VTMGVVAATE AGIPALLKPL LDHGFGSHGS 70 80 90 100 110 120 DSAKWYVPIA VIGLALVRGV SQYTSNYLLN YVSNRILLQL RLEMFQRMIH TGASFFQRET 130 140 150 160 170 180 ASTVINAIVF EVNQILSVLT GVMVTLVRDS LTVIFLLGYL FYLNWRLTLI VAVILPGIGW 190 200 210 220 230 240 LVSKINRRLR RLNREHQTLT NELSYIVEET VGGYKVVKVH NGEAYEMDRF TTMSKRLRGY 250 260 270 280 290 300 AMRMTISGGL AQPLTQFLAS IALAVVITIA VVQSSNDQTT VGGFVAFVTS MLLVISPLKH 310 320 330 340 350 360 LIDVNQPLQR GMTAAELIFG LIDEPAEPQG GGRPLSQARG EIEFRAVSFD YGAAERPTLD 370 380 390 400 410 420 RISFKVAPGE MIALAGPSGS GKTTLVNLLP RFFDPTDGTI LVDGVPVSDY DLHALRSQMA 430 440 450 460 470 480 MVSQDVVLFN DTIAANVAYG QTPDRARVQA ALEAANLADA VAAMPDGLDT LVGGNGMRLS 490 500 510 520 530 540 GGQRQRLAIA RAIYKDAPIL ILDEATSALD SESERHVQAA LERLMEGRTT LVIAHRLSTI 550 560 570 580 ERADRILVLE AGKIVEEGSH DELLRHGGLY AHLHRIQYQQ QAA

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000458 Genomic DNA. Translation: ABK09058.1.
RefSeq	YP_835951.1.
3D structure databases
SMR	A0K981. Positions 11-577.
ModBase	Search...
Protein-protein interaction databases
STRING	A0K981.
Genome annotation databases
GeneID	4449780.
GenomeReviews	Gene locus Bcen2424_2307 in contig CP000458_GR.
KEGG	bch:Bcen2424_2307.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1132.
HOGENOM	HBG758042.
OMA	HGSDSAK.
ProtClustDB	CLSK897250.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR011917. ABC_transpr_lipidA. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 1 hit.
TIGRFAMs	TIGR02203. MsbA_lipidA. 1 hit.
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51239. MSBA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0K981_BURCH

Accession

Primary (citable) accession number: A0K981

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	March 2, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)