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A0K731

- LFTR_BURCH

UniProt

A0K731 - LFTR_BURCH

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Protein
Leucyl/phenylalanyl-tRNA--protein transferase
Gene
aat, Bcen2424_1556
Organism
Burkholderia cenocepacia (strain HI2424)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-1600-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:Bcen2424_1556
OrganismiBurkholderia cenocepacia (strain HI2424)
Taxonomic identifieri331272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000000776: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation
PRO_0000304328Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi331272.Bcen2424_1556.

Structurei

3D structure databases

ProteinModelPortaliA0K731.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiIGHAHSV.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

A0K731-1 [UniParc]FASTAAdd to Basket

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MVPWLGPDDP FPSIERALGP ATGAPGLLAA SADLLPSRLI DAYLRGIFPW    50
YSDGQPVLWW SPDPRMILVP AEFKVSPSLR KTLKRVLRAP EWEVRVDHDF 100
AGVMRACAQA PRRGQRGTWI TAEIIDAYTS LYRSGNAHSI ETWHDGRRVG 150
GLYGVSFGRM FFGESMYADV TDASKIALAA LIAHLREQRL EMIDCQQNTS 200
HLASLGGREI ARKAFVAHVR SAVAEPPIPW QFDKRVLAAL TSPAETAAPT 250
GTER 254
Length:254
Mass (Da):28,030
Last modified:December 12, 2006 - v1
Checksum:i12839F4DD54FD745
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000458 Genomic DNA. Translation: ABK08308.1.
RefSeqiYP_835201.1. NC_008542.1.

Genome annotation databases

EnsemblBacteriaiABK08308; ABK08308; Bcen2424_1556.
GeneIDi4448957.
KEGGibch:Bcen2424_1556.
PATRICi19060397. VBIBurCen15205_1567.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000458 Genomic DNA. Translation: ABK08308.1 .
RefSeqi YP_835201.1. NC_008542.1.

3D structure databases

ProteinModelPortali A0K731.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331272.Bcen2424_1556.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK08308 ; ABK08308 ; Bcen2424_1556 .
GeneIDi 4448957.
KEGGi bch:Bcen2424_1556.
PATRICi 19060397. VBIBurCen15205_1567.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi IGHAHSV.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci BCEN331272:GHR7-1600-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI2424.

Entry informationi

Entry nameiLFTR_BURCH
AccessioniPrimary (citable) accession number: A0K731
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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