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A0K5P0 (DADA_BURCH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:Bcen2424_1064
OrganismBurkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]
Taxonomic identifier331272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202

Cofactor

FAD By similarity. HAMAP MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 428428D-amino acid dehydrogenase small subunit HAMAP MF_01202
PRO_1000066073

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
A0K5P0 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 75D869F846242440

FASTA42845,875
        10         20         30         40         50         60 
MRVVILGSGV VGVASAYYLA RAGHEVTVID REAGPALETS FANAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAVKWMFE KHAPLAIRLD GTRFQLQWMV QMLRNCTAER YAVNKGRMVR LAEYSRDCLQ 

       130        140        150        160        170        180 
ALRADTGIQY EGRTGGTLQL FRTQQQLDGA AKDIAVLQEA NVPFELLSPA ELKHAEPALA 

       190        200        210        220        230        240 
AVSHKLTGGL RLPGDETGDC QLFTTRLAAL AESLGVKFRY NTPIDALAIA GGKIAGVQCG 

       250        260        270        280        290        300 
SETVRADAYV VALGSYSTNF ISNLMKIPVY PLKGYSITAP IVDAAAAPVS TVLDETYKIA 

       310        320        330        340        350        360 
ITRFDQRIRV GGMAEIVGFD KTLRAARRET LEMCVNDLFP GGGDTSKATF WTGLRPMTPD 

       370        380        390        400        410        420 
GTPIVGRTPV SNLFLNTGHG TLGWTMSCGS GQLLADLISG KKPAIQADDL SVHRYLKDAP 


GQTRPAYA

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI2424.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000458 Genomic DNA. Translation: ABK07817.1.
RefSeqYP_834710.1. NC_008542.1.

3D structure databases

ProteinModelPortalA0K5P0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0K5P0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4451126.
GenomeReviewsGene locus Bcen2424_1064 in contig CP000458_GR.
KEGGbch:Bcen2424_1064.
PATRIC19059362. VBIBurCen15205_1064.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHBG729204.
OMAVDRQPAV.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycBCEN331272:BCEN2424_1064-MONOMER.

Family and domain databases

HAMAPMF_01202. DadA.
[Tree]
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
KOK00285.
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_BURCH
AccessionPrimary (citable) accession number: A0K5P0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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