A0K4V9 (A0K4V9_BURCH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL ABK07536.1
EC=3.5.1.- EMBL ABK07536.1

Gene names

Ordered Locus Names:

Bcen2424_0783

Organism

Burkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]

Taxonomic identifier

331272 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL ABK07536.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0K4V9 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 6CFFD643AF4C9387	FASTA	305	33,299
	10 20 30 40 50 60 MSAPTGWATR QGTLARPLTI DGHGLHTGRR VGVRILPARP EDGVTGIVFR RVEHGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGIGVRTIEH LLASLLACEI DHAIVELDAE EVPILDGSAT 130 140 150 160 170 180 PWVHAIRACG RVALDAPKRF IRVLRPIVVT DGDGDQRREM RIEPASRYEL SVRNDLRGFG 190 200 210 220 230 240 DMHWDGALTP AAFATDIAPS RSYGRVKWAV PAIVAGYLRG VPILRGARPS CTASIVGNRV 250 260 270 280 290 300 LGGMRLPEEF VRHRVLDLVG DLALAGAPLL ARVSALRPSH EMNFRLVDAL LAAPDAWQWA EFFET

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000458 Genomic DNA. Translation: ABK07536.1.
RefSeq	YP_834429.1. NC_008542.1.
3D structure databases
ProteinModelPortal	A0K4V9.
ModBase	Search...
Protein-protein interaction databases
STRING	A0K4V9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4448696.
GenomeReviews	Gene locus Bcen2424_0783 in contig CP000458_GR.
KEGG	bch:Bcen2424_0783.
PATRIC	19058785. VBIBurCen15205_0785.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

A0K4V9_BURCH

Accession

Primary (citable) accession number: A0K4V9

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)