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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

Arth_4026

Organism
Arthrobacter sp. (strain FB24)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciASP290399:GHIF-4082-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:Arth_4026Imported
OrganismiArthrobacter sp. (strain FB24)Imported
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeArthrobacter
Proteomesi
  • UP000000754 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290399.Arth_4026

Structurei

3D structure databases

ProteinModelPortaliA0K281
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 78Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini232 – 269Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiENOG4107RN0 Bacteria
COG0508 LUCA
HOGENOMiHOG000281564
KOiK00627
OMAiDNLCEVQ
OrthoDBiPOG091H05OF

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

A0K281-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVNKFNLPD VGEGLTEAEI VSWNVKPGDS VAINDILCEI ETAKSLVELP
60 70 80 90 100
SPFAGTVTEL LVPVGVTVDV GTPIISVSDA VSGDPTPADA PVPVAPAAAA
110 120 130 140 150
QTPAAPTANA PMYGKLFEDH DEQDSGTPGA QAVPASGKAV GPLVGSGPKA
160 170 180 190 200
DAVKRRPRKA SPSAAVLPAP AAATSPVVEP APLAEPVETQ GIWINAGAAS
210 220 230 240 250
ASGTPDTAGV PEEASGRPTL GGTISGLVNR VLAKPPVRKI ARDLGIDLAD
260 270 280 290 300
VVATGARGEV TREDLVSYQA QRDAEVDKAD TFWGKSGRPQ DQRIERIPVK
310 320 330 340 350
GVRKATAKAM VESAFAAPHV SIFVDVDASR TMEFVKRLKV SRDFEGIKVS
360 370 380 390 400
PLLILAKAVI WAAARNPSVN ATWVDSADGS DTAEIHVKHF MNLGIAAATP
410 420 430 440 450
RGLMVPNIKN AQDLSLKELA LALNDLATTA RAGKTRPAEM QGGTLTVTNI
460 470 480 490 500
GALGIDTGTP IINPGEVAIV AFGTIKQKPW VLDGEVIPRW ITTLGGSFDH
510 520
RVVDGDLSAR FMADVAAILE EPALLLD
Length:527
Mass (Da):54,583
Last modified:December 12, 2006 - v1
Checksum:i8FE81945800D8BBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA Translation: ABK05401.1
RefSeqiWP_011693849.1, NC_008541.1

Genome annotation databases

EnsemblBacteriaiABK05401; ABK05401; Arth_4026
KEGGiart:Arth_4026

Similar proteinsi

Entry informationi

Entry nameiA0K281_ARTS2
AccessioniPrimary (citable) accession number: A0K281
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health