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Reviewed, UniProtKB/Swiss-Prot A0K1I7 (TRMB_ARTS2)

Last modified June 16, 2009. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    tRNA (guanine-N(7)-)-methyltransferase
    EC=2.1.1.33
Alternative name(s):
    tRNA(m7G46)-methyltransferase
Gene names
Name: trmB
Ordered Locus Names: Arth_3782
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

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Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.

Catalytic activity

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(7)-methylguanine. HAMAP MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family.

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Ontologies

Keywords
   Biological processtRNA processing
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA modification

Inferred from electronic annotation. Source: HAMAP

   Molecular functiontRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 319319tRNA (guanine-N(7)-)-methyltransferase HAMAP MF_01057
PRO_0000288119

Regions

Region298 – 3014Substrate binding Potential

Sites

Binding site1031S-adenosyl-L-methionine By similarity
Binding site1281S-adenosyl-L-methionine By similarity
Binding site1551S-adenosyl-L-methionine By similarity
Binding site1781S-adenosyl-L-methionine By similarity
Binding site1821Substrate By similarity
Binding site2141Substrate Potential

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Sequences

Sequence LengthMass (Da)Tools
A0K1I7-1 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 66612CE2339DD1A6

FASTA31934,907
        10         20         30         40         50         60 
MSESPETPEP SPAQSPEAAP EQPQAARPVT PGSQASFGTY GGRPVSFVRR GTRLQGRRQQ 

        70         80         90        100        110        120 
AWEEHSDRWA VDVPRHIANT SVHPDYVFDA EAEFGRSAPL IVEIGSGLGD AVCHAAEENP 

       130        140        150        160        170        180 
DWDFLAVEVY TPGLANTVIK INSRKLSNVR VVEANAPEVL ATMLPAGSVS EVWVFFPDPW 

       190        200        210        220        230        240 
HKSRHHKRRL IQPEFAALVA AALKPGGLFR VATDWSNYAV HVRDVMAGSA DFVNLHDGER 

       250        260        270        280        290        300 
RGPESPLTQV WQSGVESLVG GAPVKEGRAP VSTEHTGPNE GVDETGGWAP RFEGRIRTSF 

       310 
ENKAHEAGRL IFDLCYRRL

« Hide

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References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000454 Genomic DNA. Translation: ABK05157.1.
RefSeqYP_833257.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4447832.
GenomeReviewsGene locus Arth_3782 in contig CP000454_GR.
KEGGart:Arth_3782.
TIGRArth_3782.

Phylogenomic databases

OMAA0K1I7. WVFFPDP.

Family and domain databases

HAMAPMF_01057.
[Tree]
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PANTHERPTHR23417:SF1. Methyltransf_4. 1 hit.
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. CHP91. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameTRMB_ARTS2
AccessionPrimary (citable) accession number: A0K1I7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 12, 2006
Last modified: June 16, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents