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A0K0I8 (A0K0I8_ARTS2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate synthase RuleBase RU000555
EC=2.3.3.9 RuleBase RU000555
Gene names
Ordered Locus Names:Arth_3433 EMBL ABK04808.1
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP] EMBL ABK04808.1
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. RuleBase RU000555

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. RuleBase RU000555

Sequence similarities

Belongs to the malate synthase family. RuleBase RU000555

Ontologies

Keywords
   Biological processGlyoxylate bypass RuleBase RU000555
Tricarboxylic acid cycle RuleBase RU000555
   Molecular functionAcyltransferase EMBL ABK04808.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1621Proton acceptor By similarity PIRSR PIRSR001363-1
Active site4461Proton donor By similarity PIRSR PIRSR001363-1

Sequences

Sequence LengthMass (Da)Tools
A0K0I8 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 75E47461A802EDE9

FASTA53258,789
        10         20         30         40         50         60 
MALTVTDPQP IARAEEILTP KALAFVEELH KRFAGTRAEL LKARVAKREQ VARTGKLDFL 

        70         80         90        100        110        120 
SETKDVREGD WKVAPAPAAL QDRRVEMTGP ASPAKMAINA LNSGAKVWLA DLEDASTPTW 

       130        140        150        160        170        180 
ANVIDAILNL RDAATGTLSY TSPEGKEYRL RSDAPLAVVV ARPRGWHMDE HHLLLDGEHT 

       190        200        210        220        230        240 
VGALVDFGLH FFHTAKQLLL NGQGPYYYLP KMESHLEARL WNDVFVFAQD FLGIPQGTIK 

       250        260        270        280        290        300 
ATVLIETIPA AFEMDEILYE LRDHAAGLNA GRWDYLFSII KYFRDAGADF VLPDRATVAM 

       310        320        330        340        350        360 
TAPFMRAYTE LLVKTCHHRG AFAMGGMAAV IPNRREPEVT AQAFEKVRAD KTREANDGFD 

       370        380        390        400        410        420 
GSWVAHPDLV PVCREVFDSV LGERPNQLDK QRPEVHVTAD QLLDIASADG TVTEAGLRLN 

       430        440        450        460        470        480 
LYVAVAYTAV WISGNGAVAI HNLMEDAATA EISRSQVWQQ IRNKVVLADT GNTVTRELVS 

       490        500        510        520        530 
SILAQETDKL RGEVGEETFA KYYQPASELI ADICLSEDYT DFLTTPAYEL VG

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24 EMBL ABK04808.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK04808.1.
RefSeqYP_832908.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0K0I8.
ModBaseSearch...

Protein-protein interaction databases

STRING290399.Arth_3433.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK04808; ABK04808; Arth_3433.
GeneID4444163.
KEGGart:Arth_3433.
PATRIC21002337. VBIArtSp72239_3846.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHOG000238464.
KOK01638.
OMARHVDIGD.
ProtClustDBPRK09255.

Enzyme and pathway databases

BioCycASP290399:GHIF-3495-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

InterProIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001363. Malate_synth. 1 hit.
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01344. malate_syn_A. 1 hit.
PROSITEPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0K0I8_ARTS2
AccessionPrimary (citable) accession number: A0K0I8
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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