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A0JZZ4 (ACKA_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:Arth_3238
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length386 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 386386Acetate kinase HAMAP MF_00020
PRO_1000002206

Sequences

Sequence LengthMass (Da)Tools
A0JZZ4 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 8727D98D6F599CB9

FASTA38640,770
        10         20         30         40         50         60 
MLVLVINSGS SSLKYQVRDV ASHSVLTEGL IEKIGMGNGG EGDGEIEGPR DHAEALEQVD 

        70         80         90        100        110        120 
AAIHEVLGDR TLDAVGHRVV HGGERFGEPV LIDNEITRAI ERLNPLAPLH NPANVLGIRA 

       130        140        150        160        170        180 
IAKKWPDMPQ VAVFDTAFHR TLPEHAWRYA VPDSLYTNHG IRRYGFHGTS HEYVSHQAAA 

       190        200        210        220        230        240 
LLDLPVEEFD GVIAHLGNGA SVTAIRGGKS VDTSMGFTPL EGLVMGTRSG DLDPSILVFL 

       250        260        270        280        290        300 
GRAGWSTEDI DSLLNRESGL KGLAGNNDMR SVVEASEAGD ARAATALAVA SYRLAKYIGG 

       310        320        330        340        350        360 
YHVAVGGAKA LVFTAGIGEN SHLFRALVGD KLGALGVELD AGLNSQRSKE PRVISTAASL 

       370        380 
IPVLVVPTDE ERAIAEATAA VVHSAS

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK04614.1.
RefSeqYP_832714.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JZZ4.
SMRA0JZZ4. Positions 1-383.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0JZZ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4444019.
GenomeReviewsGene locus Arth_3238 in contig CP000454_GR.
KEGGart:Arth_3238.
PATRIC21001911. VBIArtSp72239_3634.
TIGRArth_3238.

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMAERMINHA.
PhylomeDBA0JZZ4.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycASP1667:ARTH_3238-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_ARTS2
AccessionPrimary (citable) accession number: A0JZZ4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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