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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Arthrobacter sp. (strain FB24)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciASP290399:GHIF-3051-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:Arth_2984
OrganismiArthrobacter sp. (strain FB24)
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeArthrobacter
Proteomesi
  • UP000000754 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11711171DNA-directed RNA polymerase subunit betaPRO_0000300278Add
BLAST

Proteomic databases

PRIDEiA0JZ93.

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi290399.Arth_2984.

Structurei

3D structure databases

ProteinModelPortaliA0JZ93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 4 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JZ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVASSTSNVN NATAINADST DGATRRLSFA KIHEPLDVPN LLALQTDSFD
60 70 80 90 100
WLVGNERWQA RVAKAVEEGD LSVATSSGLS DIFEEISPIE DFQGTMSLSF
110 120 130 140 150
SDPEFADPKY TMAECKDRDA TYSAPLYVKA EFMNNNTGEI KQQTVFMGDF
160 170 180 190 200
PLMTEKGTFV VNGTERVVVS QLVRSPGAYF ERTADKTSDK DIFTAKIIPS
210 220 230 240 250
RGAWFELEID KRDQVGVRLD RKRKQSVTVL LKALGWTEGQ ILEEFGQYDS
260 270 280 290 300
MRATLEKDAT ETREDALLDI YRKLRPGEPP TVEAAQSLLD NLYFNSKRYD
310 320 330 340 350
LAKVGRYKIN RKLGIDRSLG DKEASVLHVE DIVAMIKFLV ALHAGEKTLT
360 370 380 390 400
GKRDGQDHEL RVEIDDIDHF GNRRIRAVGE LIENQVRTGL SRMERVVRER
410 420 430 440 450
MTTQDVEAIT PQTLINIRPV VAAIKEFFGT SQLSQFMDQN NPLSGLTHKR
460 470 480 490 500
RLSALGPGGL SRDRAGMEVR DVHPSHYGRM CPIETPEGPN IGLIGSLASY
510 520 530 540 550
GRINPFGFIE TPYRLVSEGV VSDEVQYLTA DDEAEVLIAQ ANAPLDENKK
560 570 580 590 600
FAEETVLVRA RGGGGEPVLV PAADVEFMDV SPRQMVSVAT ALIPFLEHDD
610 620 630 640 650
ANRALMGANM QRQAVPLVRS EAPFVGTGME RAAAVDAGDV VIAKKAGVVT
660 670 680 690 700
EVSAELVIML NDDGTETNYR INKFARSNQG NCYNHRVLVS EGQRLEVGGI
710 720 730 740 750
IADGPATDQG ELALGKNLLV AFMSWEGHNF EDAIILSQRI VAEDVLSSIH
760 770 780 790 800
IEEHEIDARD TKLGAEEITR DIPNVSEEVL AGLDERGIIH IGAEVEAGDI
810 820 830 840 850
LVGKVTPKGE TELTPEERLL RAIFGEKSRE VRDTSLKVPH GESGTVIGVR
860 870 880 890 900
VFDRDNDDEL PPGVNQLVRV YVAAKRKITD GDKLAGRHGN KGVISKILPI
910 920 930 940 950
EDMPFLADGT PVDIVLNPLG VPGRMNVGQV LETHLGWVAK TGWKIEGEPE
960 970 980 990 1000
WVKQLPNLPR ESGSTTVATP VFDGAREEEI TGLLDSTNVT RDGDRLINSS
1010 1020 1030 1040 1050
GKTRLFDGRS GEPFPDPISV GYMYILKLHH LVDDKIHARS TGPYSMITQQ
1060 1070 1080 1090 1100
PLGGKAQFGG QRFGEMEVWA LEAYGAAYTL QELLTIKSDD IHGRVKVYEA
1110 1120 1130 1140 1150
IVKGENIPEP GVPESFKVLI KEMQSLCLNV EVLSTDGTTI EMRDSDDAVF
1160 1170
TAAEELGIDL SRAEPSSVEE V
Length:1,171
Mass (Da):128,726
Last modified:December 12, 2006 - v1
Checksum:i526EDE3873387C02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK04363.1.
RefSeqiWP_011692816.1. NC_008541.1.

Genome annotation databases

EnsemblBacteriaiABK04363; ABK04363; Arth_2984.
KEGGiart:Arth_2984.
PATRICi21001383. VBIArtSp72239_3374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK04363.1.
RefSeqiWP_011692816.1. NC_008541.1.

3D structure databases

ProteinModelPortaliA0JZ93.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290399.Arth_2984.

Proteomic databases

PRIDEiA0JZ93.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK04363; ABK04363; Arth_2984.
KEGGiart:Arth_2984.
PATRICi21001383. VBIArtSp72239_3374.

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Enzyme and pathway databases

BioCyciASP290399:GHIF-3051-MONOMER.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 4 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FB24.

Entry informationi

Entry nameiRPOB_ARTS2
AccessioniPrimary (citable) accession number: A0JZ93
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 12, 2006
Last modified: July 6, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.