A0JYM4 (A0JYM4_ARTS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Porphobilinogen synthase EMBL ABK04144.1
EC=4.2.1.24 EMBL ABK04144.1

Gene names

Ordered Locus Names:

Arth_2765

Organism

Arthrobacter sp. (strain FB24) [Complete proteome] [HAMAP] EMBL ABK04144.1

Taxonomic identifier

290399 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5
Molecular function	Lyase EMBL ABK04144.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	197	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	249	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	234	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	207	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	218	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	275	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	314	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	A0JYM4 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 3190220F13E2C008	FASTA	327	35,085
	10 20 30 40 50 60 MSFPTHRPRR LRTTPAMRRM TAENRLAAPE LILPAFIREG LTEPNPIASM PGVVQHTTDS 70 80 90 100 110 120 LKKAAAEAVE LGVGGIMLFG IPAERDARGT ASLDPDGVLN KAIRDVRAEV GDDLVVMSDV 130 140 150 160 170 180 CLDEFTDHGH CGVLDDEGYV DNDATLEIYA AMAVAQADAG AHMLGPSGMM DGQIGVIRQA 190 200 210 220 230 240 LEDAGHTNTA VVAYAAKYAS AFYGPFREAV DSQLKGDRRT YQMDSANRRE ALLEVELDLA 250 260 270 280 290 300 EGADLVMVKP AMSYLDILAD VAAISTVPVA AYQISGEYSM IEAAAANGWI DRRAAITESV 310 320 LGIKRAGANM VLTYWASELA GWLKESR

References

[1]

"Complete sequence of chromosome 1 of Arthrobacter sp. FB24." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FB24.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000454 Genomic DNA. Translation: ABK04144.1.
RefSeq	YP_832244.1. NC_008541.1.
3D structure databases
ProteinModelPortal	A0JYM4.
ModBase	Search...
Protein-protein interaction databases
STRING	A0JYM4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4444564.
GenomeReviews	Gene locus Arth_2765 in contig CP000454_GR.
KEGG	art:Arth_2765.
PATRIC	21000923. VBIArtSp72239_3145.
TIGR	Arth_2765.
Phylogenomic databases
eggNOG	COG0113.
HOGENOM	HBG285270.
OMA	FTSHGHD.
PhylomeDB	A0JYM4.
ProtClustDB	PRK09283.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0JYM4_ARTS2

Accession

Primary (citable) accession number: A0JYM4

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)