Skip Header

Contribute Send feedback
Read comments (?) or add your own

A0JXN9 (XYLA_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:Arth_2430
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Xylose isomerase HAMAP-Rule MF_00455
PRO_1000026428

Sites

Active site541 By similarity
Active site571 By similarity
Metal binding1811Magnesium 1 By similarity
Metal binding2171Magnesium 1 By similarity
Metal binding2171Magnesium 2 By similarity
Metal binding2201Magnesium 2 By similarity
Metal binding2451Magnesium 1 By similarity
Metal binding2551Magnesium 2 By similarity
Metal binding2571Magnesium 2 By similarity
Metal binding2931Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0JXN9 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: FCEE25EBD87D6D40

FASTA39542,917
        10         20         30         40         50         60 
MTLQPTPADR FTFGLWTVGW TGADPFGVAT RPALDPVEAV HKLSELGAYG ITFHDNDLVP 

        70         80         90        100        110        120 
FDATASEREL ILKNFKAALA ETGLKTPMVT TNLFSHPVFK DGGFTSNDRS VRRFALSKVL 

       130        140        150        160        170        180 
QNIDLAAELG AETFVMWGGR EGSEYDGSKD LSAALDRMKE GVDTAAAYIK DKGYGLRIAL 

       190        200        210        220        230        240 
EPKPNEPRGD IFLPTVGHGL AFIAQLEHGD IVGLNPETGH EQMAGLNFTH GIAQALWAGK 

       250        260        270        280        290        300 
LFHIDLNGQR GIKYDQDLVF GHGDLTSAFF TVDLLENGFP NGGPKYDGPR HFDYKPSRTD 

       310        320        330        340        350        360 
GYDGVWESAK SNMSMYLLLK ERALAFRADP DVQEALKTSG VFELGEPTLA AGETTADLLA 

       370        380        390 
DASAFAEFDA DAAAQRSFAF VRLNQLAIEH LLGAR

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK03809.1.
RefSeqYP_831909.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JXN9.
SMRA0JXN9. Positions 3-395.
ModBaseSearch...

Protein-protein interaction databases

STRING290399.Arth_2430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK03809; ABK03809; Arth_2430.
GeneID4445032.
KEGGart:Arth_2430.
PATRIC21000219. VBIArtSp72239_2802.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000022596.
KOK01805.
OMADLVFGHG.
ProtClustDBPRK12677.

Enzyme and pathway databases

BioCycASP290399:GHIF-2475-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02631. xylA_Arthro. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_ARTS2
AccessionPrimary (citable) accession number: A0JXN9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents