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A0JXL2 (CLPX_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease ATP-binding subunit ClpX
Gene names
Name:clpX
Ordered Locus Names:Arth_2403
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP By similarity. HAMAP-Rule MF_00175

Subunit structure

Heterodimer of ClpP and ClpX By similarity. HAMAP-Rule MF_00175

Sequence similarities

Belongs to the ClpX chaperone family.

Ontologies

Keywords
   DomainZinc-finger
   LigandATP-binding
Metal-binding
Nucleotide-binding
Zinc
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleoside-triphosphatase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 429429ATP-dependent Clp protease ATP-binding subunit ClpX HAMAP-Rule MF_00175
PRO_1000024513

Regions

Zinc finger13 – 3826C4-type HAMAP-Rule MF_00175
Nucleotide binding127 – 1348ATP Potential

Sequences

Sequence LengthMass (Da)Tools
A0JXL2 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: EF172172D5B99044

FASTA42946,687
        10         20         30         40         50         60 
MARIGESTDL LKCSFCGKSQ KQVRKLIAGP GVYICDECIE LCNEIIEEEL AEVADLGSFE 

        70         80         90        100        110        120 
LPKPREIYDF LQEYVIGQEP AKRSLAVAVY NHYKRIQAGH APKSGSLAEG VHHDDVEIAK 

       130        140        150        160        170        180 
SNILLIGPTG CGKTYLAQTL ARRLNVPFAV ADATALTEAG YVGEDVENIL LKLIQAADYD 

       190        200        210        220        230        240 
VKKAEQGIIY IDEIDKISRK SENPSITRDV SGEGVQQALL KILEGTVASV PPQGGRKHPH 

       250        260        270        280        290        300 
QEFIQIDTTN VLFIVAGAFA GLEDIIGSRS GRKGIGFGAP LNEVKNNSDS YGEVMPEDLL 

       310        320        330        340        350        360 
KFGLIPEFIG RLPVITTVSN LDRPALIQIL STPKNALVKQ YQKMFQLDGV ELLFDDEALD 

       370        380        390        400        410        420 
VIADQALERG TGARGLRAIM EEVLLPVMFD LPSRDDIASV VITADVVAKK APPTMIAHDV 


VAKRRNKSA 

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000454 Genomic DNA. Translation: ABK03782.1.
RefSeqYP_831882.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JXL2.
SMRA0JXL2. Positions 7-50.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290399.Arth_2403.

Proteomic databases

PRIDEA0JXL2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK03782; ABK03782; Arth_2403.
GeneID4445002.
KEGGart:Arth_2403.
PATRIC21000157. VBIArtSp72239_2774.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1219.
HOGENOMHOG000010093.
KOK03544.
OMALDTMFDL.
OrthoDBEOG625JZK.
ProtClustDBPRK05342.

Enzyme and pathway databases

BioCycASP290399:GHIF-2451-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00175. ClpX.
InterProIPR003593. AAA+_ATPase.
IPR013093. ATPase_AAA-2.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
[Graphical view]
PfamPF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00382. clpX. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCLPX_ARTS2
AccessionPrimary (citable) accession number: A0JXL2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families