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A0JXJ7 (A0JXJ7_ARTS2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:Arth_2388
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP] EMBL ABK03767.1
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain298 – 37679PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A0JXJ7 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 90E28750F0ADC5E3

FASTA39040,982
        10         20         30         40         50         60 
MRSEPPHVTD NSAIVIEEPR TDDRSMLARA RRIVVKVGSS SLTSLKGGIS EEALIELSDA 

        70         80         90        100        110        120 
LAAKHNGGTE IILVSSGAIS AGLAPLGLVK RPRDLATQQA AASVGQGLLM ARYTHAFAAH 

       130        140        150        160        170        180 
GVTVSQVLLT ADDLMRRSHH MNAFRALNRL LNLGVVPVVN ENDTVATHKI RFGDNDRLSA 

       190        200        210        220        230        240 
LVAHLVRADA LVLLSDVDSL YDGPPSKGAK RIPQVDGPQD LEGVNIGKPG QAGVGTGGMQ 

       250        260        270        280        290        300 
TKVEAATMAA DSGIPALVTS TANAAAALNG EDVGTWFSVN SGRKSVRMMW LAHLAHVQGR 

       310        320        330        340        350        360 
LLLDDGAVTA VRDHRFSLLP AGITAVEGTF ESGDAVEMVS PDGTVIARGL VNYSSDELPQ 

       370        380        390 
MLGRSTVELG ESLGRGFDRE VVHVDDLVLV

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK03767.1.
RefSeqYP_831867.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JXJ7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0JXJ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4444971.
GenomeReviewsGene locus Arth_2388 in contig CP000454_GR.
KEGGart:Arth_2388.
PATRIC21000127. VBIArtSp72239_2759.
TIGRArth_2388.

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHBG507643.
OMATFGDNDM.
PhylomeDBA0JXJ7.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0JXJ7_ARTS2
AccessionPrimary (citable) accession number: A0JXJ7
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info