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A0JX84 (AROC_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Arth_2274
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Chorismate synthase HAMAP MF_00300
PRO_0000322387

Sequences

Sequence LengthMass (Da)Tools
A0JX84 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 30C827C2CE46A149

FASTA39941,895
        10         20         30         40         50         60 
MLRWLTAGES HGPALVGIIE GVPAGVELTS SQIADALARR RLGYGRGARM KFEQDVVTVL 

        70         80         90        100        110        120 
GGVRHGITQG GPVAIQVGNT EWPKWEQIMA ADPVAPEILA DQARNAPLTR PRPGHADFTG 

       130        140        150        160        170        180 
MQKYGFDEAR PVLERASARE TATRVALGTV ASQFLKQLGI ELVSHTVSIA SVSVPEGRPL 

       190        200        210        220        230        240 
PVPANVIALD ADPLRCFDRE TSDAMVAEVD AAHKEGETLG GVVEVLAYGL PPGLGSYVHW 

       250        260        270        280        290        300 
DRRLDSRLAA ALMGIQAIKG VEVGDGFLTA SRRGSAAHDE IVKDSDGRII RTSNRAGGIE 

       310        320        330        340        350        360 
GGMSIGDVLR VRAAMKPIAT VPRALKTIDV STGEAAKAHH QRSDVCAVPA AGVVAEAMVA 

       370        380        390 
LVLAEAVAEK FGGDSVAETA RNIKGYLDNI PASLDSIGQ

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK03654.1.
RefSeqYP_831754.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JX84.
SMRA0JX84. Positions 1-386.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0JX84.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4445317.
GenomeReviewsGene locus Arth_2274 in contig CP000454_GR.
KEGGart:Arth_2274.
PATRIC20999891. VBIArtSp72239_2643.
TIGRArth_2274.

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycASP1667:ARTH_2274-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ARTS2
AccessionPrimary (citable) accession number: A0JX84
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 12, 2006
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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