Skip Header

Contribute Send feedback
Read comments (?) or add your own

A0JX82 (AROB_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Arth_2272
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3633633-dehydroquinate synthase HAMAP MF_00110
PRO_1000094453

Sequences

Sequence LengthMass (Da)Tools
A0JX82 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: F825AA32B0CC88AD

FASTA36338,981
        10         20         30         40         50         60 
MSSESTVIKV TGKSAADNYD VVVGRGLLGR LPELLGERVK RVLVIHPRAL RLTGDTVRDE 

        70         80         90        100        110        120 
LASAGFTALT AEIPDAEEGK HIQVAAFCWQ VLGQNDFTRS DAVVAVGGGA VTDLAGFVAA 

       130        140        150        160        170        180 
TWLRGVKVIH MPTSLLGMVD ASVGGKTGIN TAEGKNLVGA FHPPAAVLAD LDTLSTLPKN 

       190        200        210        220        230        240 
ELISGMAEVI KCGFIADPAI LDLVEKDPSA VTDPQSAFLR ELIERAIAVK ADVVSEDLKE 

       250        260        270        280        290        300 
TGRREILNYG HTLGHAIELV ERYSWRHGAA VSVGMMFAAE LARSVGRLSD ADADRHRTIL 

       310        320        330        340        350        360 
ETLGLPITYR RDRWQGLLDG MRRDKKSRGD LLRFVVLDGI ARPGILDVPD TSLLFAAYQE 


IAS

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK03652.1.
RefSeqYP_831752.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JX82.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0JX82.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4445315.
GenomeReviewsGene locus Arth_2272 in contig CP000454_GR.
KEGGart:Arth_2272.
PATRIC20999887. VBIArtSp72239_2641.
TIGRArth_2272.

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAWMRGVRV.
PhylomeDBA0JX82.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycASP1667:ARTH_2272-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_ARTS2
AccessionPrimary (citable) accession number: A0JX82
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: December 12, 2006
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents