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A0JWP8

- PGK_ARTS2

UniProt

A0JWP8 - PGK_ARTS2

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Arthrobacter sp. (strain FB24)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391SubstrateUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation
Binding sitei161 – 1611SubstrateUniRule annotation
Binding sitei211 – 2111ATPUniRule annotation
Binding sitei307 – 3071ATP; via carbonyl oxygenUniRule annotation
Binding sitei338 – 3381ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi364 – 3674ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciASP290399:GHIF-2132-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Arth_2088
OrganismiArthrobacter sp. (strain FB24)
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000000754: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Phosphoglycerate kinasePRO_1000009604Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi290399.Arth_2088.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni62 – 654Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiHASVYDI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

A0JWP8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFHTLNELI ADGVRGRYIL VRSDLNVPLD GSEVTDDGRI KASLPVLTKL
60 70 80 90 100
TDAGARVLVT AHLGRPKGAP EEKYSLKPAA TRLAELAPFQ VTLAGDTVGA
110 120 130 140 150
SAKEHAAALQ DGEVLVLENV RFDARETSKD DAERGAFADE LVSLTGENGA
160 170 180 190 200
FVDDAFGAVH RKHASVYDVA TRLPSYQGDL VHTEVEVLRK LTTETQRPYV
210 220 230 240 250
VVLGGSKVSD KLAVIDNLIG KADTILVGGG MLFTFLAADG HKVAGSLLEE
260 270 280 290 300
DQIPVVQDYL KRAADAGTEF VVPTDVVVAA KFAADADHET VRADAIEGSS
310 320 330 340 350
FGAQGIGLDI GPESAAEFAN RIKGAKTVFW NGPMGVFEFD AFAGGTRAIA
360 370 380 390 400
LALTEADAFT VVGGGDSAAA VRTLGFADDQ FGHISTGGGA SLEYLEGKEL

PGLSVLDR
Length:408
Mass (Da):42,808
Last modified:December 12, 2006 - v1
Checksum:iF1F30B5DA56066F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK03468.1.
RefSeqiWP_011691934.1. NC_008541.1.
YP_831568.1. NC_008541.1.

Genome annotation databases

EnsemblBacteriaiABK03468; ABK03468; Arth_2088.
GeneIDi4445392.
KEGGiart:Arth_2088.
PATRICi20999511. VBIArtSp72239_2454.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK03468.1 .
RefSeqi WP_011691934.1. NC_008541.1.
YP_831568.1. NC_008541.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290399.Arth_2088.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK03468 ; ABK03468 ; Arth_2088 .
GeneIDi 4445392.
KEGGi art:Arth_2088.
PATRICi 20999511. VBIArtSp72239_2454.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi HASVYDI.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci ASP290399:GHIF-2132-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FB24.

Entry informationi

Entry nameiPGK_ARTS2
AccessioniPrimary (citable) accession number: A0JWP8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3