Reviewed, UniProtKB/Swiss-Prot A0JWP8 (PGK_ARTS2)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase
    EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Arth_2088

Organism

Arthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]

Taxonomic identifier

290399 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity. HAMAP MF_00145
Subcellular location	Cytoplasm Potential HAMAP MF_00145.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 408	408	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000009604
Regions
	Nucleotide binding	364 – 367	4	ATP By similarity
	Region	24 – 26	3	Substrate binding By similarity
	Region	62 – 65	4	Substrate binding By similarity
Sites
	Binding site	39	1	Substrate By similarity
	Binding site	121	1	Substrate By similarity
	Binding site	161	1	Substrate By similarity
	Binding site	211	1	ATP By similarity
	Binding site	307	1	ATP; via carbonyl oxygen By similarity
	Binding site	338	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0JWP8-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: F1F30B5DA56066F1	FASTA	408	42,808
	10 20 30 40 50 60 MTFHTLNELI ADGVRGRYIL VRSDLNVPLD GSEVTDDGRI KASLPVLTKL TDAGARVLVT 70 80 90 100 110 120 AHLGRPKGAP EEKYSLKPAA TRLAELAPFQ VTLAGDTVGA SAKEHAAALQ DGEVLVLENV 130 140 150 160 170 180 RFDARETSKD DAERGAFADE LVSLTGENGA FVDDAFGAVH RKHASVYDVA TRLPSYQGDL 190 200 210 220 230 240 VHTEVEVLRK LTTETQRPYV VVLGGSKVSD KLAVIDNLIG KADTILVGGG MLFTFLAADG 250 260 270 280 290 300 HKVAGSLLEE DQIPVVQDYL KRAADAGTEF VVPTDVVVAA KFAADADHET VRADAIEGSS 310 320 330 340 350 360 FGAQGIGLDI GPESAAEFAN RIKGAKTVFW NGPMGVFEFD AFAGGTRAIA LALTEADAFT 370 380 390 400 VVGGGDSAAA VRTLGFADDQ FGHISTGGGA SLEYLEGKEL PGLSVLDR

References

[1]

"Complete sequence of chromosome 1 of Arthrobacter sp. FB24." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000454 Genomic DNA. Translation: ABK03468.1.
RefSeq	YP_831568.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0JWP8.
Genome annotation databases
GeneID	4445392.
GenomeReviews	Gene locus Arth_2088 in contig CP000454_GR.
KEGG	art:Arth_2088.
TIGR	Arth_2088.
Phylogenomic databases
eggNOG	COG0126.
HOGENOM	HBG453500.
OMA	RFNAGET.
Family and domain databases
HAMAP	MF_00145. Phosphoglyc_kinase. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_ARTS2

Accession

Primary (citable) accession number: A0JWP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 12, 2006
Last modified:	January 19, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)