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A0JV94 (MURG_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:Arth_1570
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000002615

Sequences

Sequence LengthMass (Da)Tools
A0JV94 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 04820088C897D906

FASTA36637,865
        10         20         30         40         50         60 
MNAESLSVVL AGGGTAGHIS PLLAIAAALR DVRPDVRLLA VGTPSGMETR LVPAAGLELA 

        70         80         90        100        110        120 
TISRVPFPRR PSLDLLRLPG RLAGAVKQAG RILDDAHADV LVGVGGYVCT PLYLAARRRK 

       130        140        150        160        170        180 
IPIVIHEANT RAGLANKVGA RFSHHVGVAF AGTKLRGARH VGMPMRREVS GLDRAASRHA 

       190        200        210        220        230        240 
ARELLGLDQH KPALIVTGGS SGAQSINRTI AASLDALAKA GIQTLHITGK GKSVLDGEGK 

       250        260        270        280        290        300 
PLAADGYRQV EYVDGMENVY AAADLLLGRA GAATVCETAA VGIPAVFVPL PIGNGEQALN 

       310        320        330        340        350        360 
AAGPVQAGGA LVVDDESFTP EWVSREIIPL LSDPARLAKM AASSEALGIR NADRRMADLV 


LEAVSK

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000454 Genomic DNA. Translation: ABK02964.1.
RefSeqYP_831064.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JV94.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0JV94.

Protein family/group databases

CAZyGT28. Glycosyltransferase Family 28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4445902.
GenomeReviewsGene locus Arth_1570 in contig CP000454_GR.
KEGGart:Arth_1570.
PATRIC20998449. VBIArtSp72239_1930.
TIGRArth_1570.

Phylogenomic databases

eggNOGCOG0707.
HOGENOMHBG617076.
OMAVPLPHGN.
PhylomeDBA0JV94.
ProtClustDBPRK00726.

Enzyme and pathway databases

BioCycASP1667:ARTH_1570-MONOMER.

Family and domain databases

HAMAPMF_00033. MurG.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
KOK02563.
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. MurG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_ARTS2
AccessionPrimary (citable) accession number: A0JV94
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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