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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Arthrobacter sp. (strain FB24)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciASP290399:GHIF-1456-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Arth_1424
OrganismiArthrobacter sp. (strain FB24)
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeArthrobacter
ProteomesiUP000000754 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306tRNA pseudouridine synthase BPRO_1000084544Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290399.Arth_1424.

Structurei

3D structure databases

ProteinModelPortaliA0JUU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231225.
KOiK03177.
OMAiIMQVPSK.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR015225. tRNA_psdUridine_synth_fam2_C.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09142. TruB_C. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0JUU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSGLVIVDK PQGWTSHDVV GRMRRLAGTR KVGHAGTLDP MATGVLVLGI
60 70 80 90 100
NKATRLLTYI VGTSKTYTAT IRLGESTVTD DAEGEVVSSH SAAAVTEGAI
110 120 130 140 150
RAAVAALTGE IQQVPSSVSA IKVNGERAYA RVRSGEDVKL AARPVTIHRF
160 170 180 190 200
DVHAVRPERA GAVLDVDVTV ECSSGTYIRA LARDLGEALG TGGHLTALRR
210 220 230 240 250
TQVGPYTLDQ ARTLEQLAEE LEVLEMSQAA RALMPNRELS EDEATEISFG
260 270 280 290 300
RRIAAGAGAG TPEAATADNP AAAFAPDGSL VALLADAGGY AKPVLVFAPS

NEQPGK
Length:306
Mass (Da):31,873
Last modified:December 12, 2006 - v1
Checksum:i13BD2F21F300E941
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK02818.1.
RefSeqiWP_011691285.1. NC_008541.1.
YP_830918.1. NC_008541.1.

Genome annotation databases

EnsemblBacteriaiABK02818; ABK02818; Arth_1424.
KEGGiart:Arth_1424.
PATRICi20998137. VBIArtSp72239_1778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA. Translation: ABK02818.1.
RefSeqiWP_011691285.1. NC_008541.1.
YP_830918.1. NC_008541.1.

3D structure databases

ProteinModelPortaliA0JUU8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290399.Arth_1424.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK02818; ABK02818; Arth_1424.
KEGGiart:Arth_1424.
PATRICi20998137. VBIArtSp72239_1778.

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231225.
KOiK03177.
OMAiIMQVPSK.
OrthoDBiEOG6358D3.

Enzyme and pathway databases

BioCyciASP290399:GHIF-1456-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR015225. tRNA_psdUridine_synth_fam2_C.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09142. TruB_C. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FB24.

Entry informationi

Entry nameiTRUB_ARTS2
AccessioniPrimary (citable) accession number: A0JUU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 12, 2006
Last modified: June 24, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.