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A0JUU8 (TRUB_ARTS2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B

EC=5.4.99.25
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name=Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene names
Name:truB
Ordered Locus Names:Arth_1424
OrganismArthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]
Taxonomic identifier290399 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306tRNA pseudouridine synthase B HAMAP-Rule MF_01080
PRO_1000084544

Sites

Active site391Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
A0JUU8 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 13BD2F21F300E941

FASTA30631,873
        10         20         30         40         50         60 
MLSGLVIVDK PQGWTSHDVV GRMRRLAGTR KVGHAGTLDP MATGVLVLGI NKATRLLTYI 

        70         80         90        100        110        120 
VGTSKTYTAT IRLGESTVTD DAEGEVVSSH SAAAVTEGAI RAAVAALTGE IQQVPSSVSA 

       130        140        150        160        170        180 
IKVNGERAYA RVRSGEDVKL AARPVTIHRF DVHAVRPERA GAVLDVDVTV ECSSGTYIRA 

       190        200        210        220        230        240 
LARDLGEALG TGGHLTALRR TQVGPYTLDQ ARTLEQLAEE LEVLEMSQAA RALMPNRELS 

       250        260        270        280        290        300 
EDEATEISFG RRIAAGAGAG TPEAATADNP AAAFAPDGSL VALLADAGGY AKPVLVFAPS 


NEQPGK 

« Hide

References

[1]"Complete sequence of chromosome 1 of Arthrobacter sp. FB24."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FB24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000454 Genomic DNA. Translation: ABK02818.1.
RefSeqYP_830918.1. NC_008541.1.

3D structure databases

ProteinModelPortalA0JUU8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290399.Arth_1424.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK02818; ABK02818; Arth_1424.
GeneID4446060.
KEGGart:Arth_1424.
PATRIC20998137. VBIArtSp72239_1778.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231225.
KOK03177.
OMAPKNISSA.
OrthoDBEOG6358D3.

Enzyme and pathway databases

BioCycASP290399:GHIF-1456-MONOMER.

Family and domain databases

HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR015225. tRNA_psdUridine_synth_fam2_C.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF09142. TruB_C. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUB_ARTS2
AccessionPrimary (citable) accession number: A0JUU8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families