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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Arthrobacter sp. (strain FB24)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei39NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Arth_1424
OrganismiArthrobacter sp. (strain FB24)
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeArthrobacter
Proteomesi
  • UP000000754 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000845441 – 306tRNA pseudouridine synthase BAdd BLAST306

Interactioni

Protein-protein interaction databases

STRINGi290399.Arth_1424

Structurei

3D structure databases

ProteinModelPortaliA0JUU8
SMRiA0JUU8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

Gene3Di2.30.130.10, 1 hit
HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR015947 PUA-like_sf
IPR036974 PUA_sf
IPR015225 tRNA_psdUridine_synth_fam2_C
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09142 TruB_C, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A0JUU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSGLVIVDK PQGWTSHDVV GRMRRLAGTR KVGHAGTLDP MATGVLVLGI
60 70 80 90 100
NKATRLLTYI VGTSKTYTAT IRLGESTVTD DAEGEVVSSH SAAAVTEGAI
110 120 130 140 150
RAAVAALTGE IQQVPSSVSA IKVNGERAYA RVRSGEDVKL AARPVTIHRF
160 170 180 190 200
DVHAVRPERA GAVLDVDVTV ECSSGTYIRA LARDLGEALG TGGHLTALRR
210 220 230 240 250
TQVGPYTLDQ ARTLEQLAEE LEVLEMSQAA RALMPNRELS EDEATEISFG
260 270 280 290 300
RRIAAGAGAG TPEAATADNP AAAFAPDGSL VALLADAGGY AKPVLVFAPS

NEQPGK
Length:306
Mass (Da):31,873
Last modified:December 12, 2006 - v1
Checksum:i13BD2F21F300E941
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA Translation: ABK02818.1

Genome annotation databases

EnsemblBacteriaiABK02818; ABK02818; Arth_1424
KEGGiart:Arth_1424

Similar proteinsi

Entry informationi

Entry nameiTRUB_ARTS2
AccessioniPrimary (citable) accession number: A0JUU8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health