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A0JTY2

- A0JTY2_ARTS2

UniProt

A0JTY2 - A0JTY2_ARTS2

Protein

Alanine racemase

Gene

Arth_1108

Organism
Arthrobacter sp. (strain FB24)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei47 – 471Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei148 – 1481SubstrateUniRule annotation
    Active sitei281 – 2811Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei329 – 3291Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciASP290399:GHIF-1134-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Arth_1108Imported
    OrganismiArthrobacter sp. (strain FB24)Imported
    Taxonomic identifieri290399 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
    ProteomesiUP000000754: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei47 – 471N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi290399.Arth_1108.

    Structurei

    3D structure databases

    ProteinModelPortaliA0JTY2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiTHLAWAD.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0JTY2-1 [UniParc]FASTAAdd to Basket

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    MRLNAHIESA RNAALTGQVS VDLSAISDNI RTLRQRSAAP HFMAVVKGNA    50
    YGHGLVDVAR TALSAGADWL GTAQLHEAIA LRRAGITAPV LSWLYLAAAS 100
    SETIREALEY DVDVSLGSVA QLDVVAGIAR RLGRPAVVHL ELDTGLSRGG 150
    ARAEDWAELV AAARTAERDG TLSVRGVWTH LAWADVPAHP ANLAAVAAFE 200
    EAVLAARAAG LEPELRHVSS SANILDRPEF AFDMVRAGLA FYGLAPADHL 250
    APADFGLRPA LTVTAPVVLV KKVPAGTGVS YEHQAITHEP RYLGLIPLGY 300
    ADGIPKGISG RSLILLGGRR VPVIGKVCMD QFMVDLGPDA NGVAVGDTAV 350
    LFGDPRTGAA SADDWGAAIG SHGDEIINRI APRLPRAYEC PDYQEAGAPV 400
    GA 402
    Length:402
    Mass (Da):42,040
    Last modified:December 12, 2006 - v1
    Checksum:i538B48B3E9112BB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000454 Genomic DNA. Translation: ABK02502.1.
    RefSeqiWP_011690969.1. NC_008541.1.
    YP_830602.1. NC_008541.1.

    Genome annotation databases

    EnsemblBacteriaiABK02502; ABK02502; Arth_1108.
    GeneIDi4446411.
    KEGGiart:Arth_1108.
    PATRICi20997481. VBIArtSp72239_1455.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000454 Genomic DNA. Translation: ABK02502.1 .
    RefSeqi WP_011690969.1. NC_008541.1.
    YP_830602.1. NC_008541.1.

    3D structure databases

    ProteinModelPortali A0JTY2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290399.Arth_1108.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK02502 ; ABK02502 ; Arth_1108 .
    GeneIDi 4446411.
    KEGGi art:Arth_1108.
    PATRICi 20997481. VBIArtSp72239_1455.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi THLAWAD.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci ASP290399:GHIF-1134-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FB24Imported.

    Entry informationi

    Entry nameiA0JTY2_ARTS2
    AccessioniPrimary (citable) accession number: A0JTY2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 12, 2006
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3