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Protein

Ribonuclease H

Gene

Arth_0781

Organism
Arthrobacter sp. (strain FB24)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.SAAS annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.SAAS annotation

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionEndonucleaseSAAS annotation, Hydrolase, Nuclease
LigandMagnesiumSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

BioCyciASP290399:GHIF-801-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease HSAAS annotation (EC:3.1.26.4SAAS annotation)
Gene namesi
Ordered Locus Names:Arth_0781Imported
OrganismiArthrobacter sp. (strain FB24)Imported
Taxonomic identifieri290399 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeArthrobacter
Proteomesi
  • UP000000754 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Subunit structurei

Monomer.SAAS annotation

Protein-protein interaction databases

STRINGi290399.Arth_0781

Structurei

3D structure databases

ProteinModelPortaliA0JT09
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 139RNase HInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the RNase H family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4108UMW Bacteria
COG0328 LUCA
HOGENOMiHOG000239486
KOiK03469
OMAiWRLRFHQ
OrthoDBiPOG091H04XT

Family and domain databases

CDDicd09278 RNase_HI_prokaryote_like, 1 hit
Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR027843 DUF4440
IPR032710 NTF2-like_dom_sf
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR022892 RNaseHI
PfamiView protein in Pfam
PF14534 DUF4440, 1 hit
PF00075 RNase_H, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
SSF54427 SSF54427, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit

Sequencei

Sequence statusi: Complete.

A0JT09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITAAADGS ALGNPGPAGW AWYVNDDCWR AGGWPHGTNN QGELMAVLDL
60 70 80 90 100
FRCTAHLPGE ELHILCDSQY VINSVTKWMP GWKRKGWRKA DGKPVLNVEI
110 120 130 140 150
LREIDQALSG RKYRFEWVRG HAGHDLNEAA DDRARAAATA YQQGIAVRSG
160 170 180 190 200
PGFVRGDGAS AAPAANAPAV RDSVAPGSSN RPDHFAEPDL FSELETDPFA
210 220 230 240 250
APTGREATPE AVVEALEREL LSPDTRADIG RTGVLLHPEF TEIGSSGRLW
260 270 280 290 300
TRDSMMMSLE ENPGGAAELE MIGAERIGAE AVLLTYRSKG REGSSLRSSL
310
WVLDGKRWRL RFHQGTPEA
Length:319
Mass (Da):34,682
Last modified:December 12, 2006 - v1
Checksum:i2F806407F025515D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000454 Genomic DNA Translation: ABK02179.1
RefSeqiWP_011690646.1, NC_008541.1

Genome annotation databases

EnsemblBacteriaiABK02179; ABK02179; Arth_0781
KEGGiart:Arth_0781

Similar proteinsi

Entry informationi

Entry nameiA0JT09_ARTS2
AccessioniPrimary (citable) accession number: A0JT09
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health