A0JSZ3 (A0JSZ3_ARTS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	Arth_0765

Organism

Arthrobacter sp. (strain FB24) [Complete proteome] [HAMAP] EMBL ABK02163.1

Taxonomic identifier

290399 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 Methyltransferase EMBL ABK02163.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0JSZ3 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 642752AF6B104B6F	FASTA	385	40,413
	10 20 30 40 50 60 MTENYTALYE EHKKLGASFT DFGGWQMPLK YSSELAEHHA VRKAAGLFDL SHMGEVWVTG 70 80 90 100 110 120 PDAAAFLDYA LVGKISAMSV GKAKYSLICQ EDGGIIDDLI VYRRPAADAA GNGTDKFLVV 130 140 150 160 170 180 PNAGNAVVVA AALAERAAKF DVVVDDASAR TSLIAVQGPK AEAILLRLVP AAQHELVTGL 190 200 210 220 230 240 KYYAAVEVPF LVAGATKDLL LARTGYTGED GFEIFVDNDD AAALWQAIGA VAEEGELVPA 250 260 270 280 290 300 GLACRDSLRL EAGMPLFGNE LSREGNPYAA GLGPVVSLAK EGDFVGRAAL EALKAGGAGA 310 320 330 340 350 360 TSGRKLVGLK GLGRRAGRSH YPVLKDGAVV GEVTSGQPSP TLGYPVALAY VDVEFSEVGT 370 380 ALDIDLRGKA EPFEVVALPF YKRQK

References

[1]

"Complete sequence of chromosome 1 of Arthrobacter sp. FB24." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FB24.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000454 Genomic DNA. Translation: ABK02163.1.
RefSeq	YP_830263.1. NC_008541.1.
3D structure databases
ProteinModelPortal	A0JSZ3.
ModBase	Search...
Protein-protein interaction databases
STRING	A0JSZ3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4446739.
GenomeReviews	Gene locus Arth_0765 in contig CP000454_GR.
KEGG	art:Arth_0765.
PATRIC	20996785. VBIArtSp72239_1111.
TIGR	Arth_0765.
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	DAIANDC.
PhylomeDB	A0JSZ3.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0JSZ3_ARTS2

Accession

Primary (citable) accession number: A0JSZ3

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)