ID   A0JSJ3_ARTS2            Unreviewed;       954 AA.
AC   A0JSJ3;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   OrderedLocusNames=Arth_0614 {ECO:0000313|EMBL:ABK02013.1};
OS   Arthrobacter sp. (strain FB24).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=290399 {ECO:0000313|EMBL:ABK02013.1, ECO:0000313|Proteomes:UP000000754};
RN   [1] {ECO:0000313|Proteomes:UP000000754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB24 {ECO:0000313|Proteomes:UP000000754};
RX   PubMed=24501649; DOI=10.4056/sigs.4438185;
RA   Nakatsu C.H., Barabote R., Thompson S., Bruce D., Detter C., Brettin T.,
RA   Han C., Beasley F., Chen W., Konopka A., Xie G.;
RT   "Complete genome sequence of Arthrobacter sp. strain FB24.";
RL   Stand. Genomic Sci. 9:106-116(2013).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC       ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR   EMBL; CP000454; ABK02013.1; -; Genomic_DNA.
DR   RefSeq; WP_011690481.1; NC_008541.1.
DR   AlphaFoldDB; A0JSJ3; -.
DR   STRING; 290399.Arth_0614; -.
DR   KEGG; art:Arth_0614; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_11; -.
DR   OrthoDB; 9768133at2; -.
DR   Proteomes; UP000000754; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW   Rule:MF_00595};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Pyruvate {ECO:0000313|EMBL:ABK02013.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000754}.
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        171
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT                   ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        607
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   954 AA;  104649 MW;  33777945F150B0D0 CRC64;
     MADTAVNPGA HLAAGTDPAG SDSSADLASE LRADVRRVST LLGESLVRQH GPELLDLVEQ
     VRLLTKESKE AARGGADATG PWSSHDVVAQ VRELLGSLPI DQATDLVRAF AFYFHLANAA
     EQVHRVRGLR TRQEKDGWLA KAVEEISGQA GPAVLQEVVN ELDVRPIFTA HPTEASRRSV
     LDKIRRLSDV LAVSTEEGTS ARRRQDRQLA EVIDQMWQTD ELRQVRPTPV DEARNAIYYL
     NSILTDAMPE MLSDLSELLG EHGVTLPSQK APIRFGSWIG GDRDGNPNVT AGVTREILQI
     QNQHAVRISI AMIDELIAIL SNSTALAGAD RELLDSIDTD LKNLPGLDRR VLELNAQEPY
     RLKLTCIKAK LLNTAKRVAA GSSHEPGRDY TSTAGVLAEL GLLEESLRNH HAGLAADGAL
     ARVRRAIASF GLHLATLDIR EHADHHHDAV GQLMDRLGGP GVRYSELSRA ERLEVLGAEL
     GSRRPLSGHP IKLDGVADGT YDVFREIRRA LKTYGPDVIE TYIISMTRGA DDVLAAAVLA
     REAGLVSLFG DAPYAKIGFA PLLETVEELR ASAEIVDQLL SDPSYRELVR LRGDVQEIML
     GYSDSNKESG VMTSQWEIHK TQRKLRDVAA KHGVRVRLFH GRGGSVGRGG GPTYDAIMAQ
     PNGVLEGEIK FTEQGEVISD KYSLPELARE NLELSLAAVM QGSALHRTPR TSEDQRERYG
     HVMETISDAA FARYRSLIDD PDLPAYFMAS TPVEQLGSLN IGSRPSKRPD SGAGLGGLRA
     IPWVFGWTQS RQIVPGWFGV GSGLKAAREA GNTEQLTEMM DRWHFFRSVL SNVEMTLAKT
     DMDIAGYYVS TLVPEELHHL FRAIREEYDL TVAEIQKLTG EHVLLDAQPT LKRSLEIRDQ
     YLDPISYLQV ELMRRMRAEG SEGESISGAE IDERLQRAML ITVNGVAAGL RNTG
//