Reviewed, UniProtKB/Swiss-Prot A0JRF5 (ARAA_ARTS2)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	Arth_0224

Organism

Arthrobacter sp. (strain FB24) [Complete proteome] [HAMAP]

Taxonomic identifier

290399 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	511 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 511	511	L-arabinose isomerase HAMAP MF_00519		PRO_0000312600
Sites
	Metal binding	316	1	Manganese By similarity
	Metal binding	343	1	Manganese By similarity
	Metal binding	360	1	Manganese By similarity
	Metal binding	459	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0JRF5-1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: EC7776D5124E501A	FASTA	511	55,716
	10 20 30 40 50 60 MSNPNYTSAN GTSLSQYEVW FLTGSQHLYG EDVLKQVAAQ SQEIADALNG SSDVPVKVVW 70 80 90 100 110 120 KPVLTDSDAI RRTALEANAD DSVIGVTAWM HTFSPAKMWI QGLDLLRKPL LHLHTQANVE 130 140 150 160 170 180 LPWADIDFDF MNLNQAAHGD REFGYIQSRL GIPRKTVVGH VSNPEVTRQV GVWQRASAGW 190 200 210 220 230 240 AAVRTLKLTR FGDNMRNVAV TEGDKTEAEL RFGVSVNTWS VNELADAVHG AAESDVDALV 250 260 270 280 290 300 AEYERLYEVV PELKAGGARH ESLRYSARIE LGLRSFLEAN GSAAFTTSFE DLGELRQLPG 310 320 330 340 350 360 MAVQRLMADG YGFGAEGDWK TAILVRAAKV MGSGLPGGAS LMEDYTYHLA PGQEKILGAH 370 380 390 400 410 420 MLEVCPSLTA TKPRVEIHPL GIGGKEDPVR MVFDTDAGPG VVVALSDMRD RFRLVANAVD 430 440 450 460 470 480 VVDLDEPLPN LPVARALWSP KPDFATSAAA WLTAGAAHHT VLSTQVGMDV FEDFAEIAKT 490 500 510 ELLTIDEGTT IRQFKKELNW NAAYYRLAGG L

References

[1]

"Complete sequence of chromosome 1 of Arthrobacter sp. FB24." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Thompson S., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Beasley F., Chen W., Jerke K., Nakatsu C.H., Richardson P. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000454 Genomic DNA. Translation: ABK01625.1.
RefSeq	YP_829725.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0JRF5.
Genome annotation databases
GeneID	4447315.
GenomeReviews	Gene locus Arth_0224 in contig CP000454_GR.
KEGG	art:Arth_0224.
TIGR	Arth_0224.
Phylogenomic databases
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_ARTS2

Accession

Primary (citable) accession number: A0JRF5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	December 12, 2006
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)